Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities

doi:10.1016/j.phytochem.2005.02.003

	Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities
	Wang, JS ; Zheng, YT ; Efferth, T ; Wang, RR ; Shen, YM ; Hao, XJ
	2005-03-01
发表期刊	PHYTOCHEMISTRY
ISSN	0031-9422
卷号	66 期号:6 页码:697-701
摘要	A diprenylated indole, (E)-3-(3-hydroxymethyl-2-butenyl)-7-(3-methyl-2-butenyl)-1H-indole (1), and six known carbazole alkaloids were isolated from the twigs and leaves of Glycosmis montana Pierre (Rutaceae). Their structures were determined on the basis of analysis of spectral evidence including 1D and 2D NMR and MS. The alkaloids (1-3) exhibited weak to moderate take in vitro inhibitory activity against HIV replication in C8166 cells, and they (as well as carbalexine A and B) had cytotoxic activity against the human leukaemia cell line CCRF-CEM. (c) 2005 Elsevier Ltd. All rights reserved.
关键词	Glycosmis Montana Rutaceae Diprenylated Indole Carbozole Anti-hiv C8166 Cytotoxicity Leukaemia
学科领域	Biochemistry & Molecular Biology ; Plant Sciences
DOI	10.1016/j.phytochem.2005.02.003
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000228403300015
引用统计	被引频次：68[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/4720
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Yunnan 650204, Peoples R China 2.Chinese Acad Sci, Kunming Inst Zool, Kunming 650223, Peoples R China 3.German Canc Res Ctr, D-69120 Heidelberg, Germany
推荐引用方式 GB/T 7714	Wang, JS,Zheng, YT,Efferth, T,et al. Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities[J]. PHYTOCHEMISTRY,2005,66(6):697-701.
APA	Wang, JS,Zheng, YT,Efferth, T,Wang, RR,Shen, YM,&Hao, XJ.(2005).Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities.PHYTOCHEMISTRY,66(6),697-701.
MLA	Wang, JS,et al."Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities".PHYTOCHEMISTRY 66.6(2005):697-701.

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