Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities
Wang, JS; Zheng, YT; Efferth, T; Wang, RR; Shen, YM; Hao, XJ
2005-03-01
发表期刊PHYTOCHEMISTRY
ISSN0031-9422
卷号66期号:6页码:697-701
摘要A diprenylated indole, (E)-3-(3-hydroxymethyl-2-butenyl)-7-(3-methyl-2-butenyl)-1H-indole (1), and six known carbazole alkaloids were isolated from the twigs and leaves of Glycosmis montana Pierre (Rutaceae). Their structures were determined on the basis of analysis of spectral evidence including 1D and 2D NMR and MS. The alkaloids (1-3) exhibited weak to moderate take in vitro inhibitory activity against HIV replication in C8166 cells, and they (as well as carbalexine A and B) had cytotoxic activity against the human leukaemia cell line CCRF-CEM. (c) 2005 Elsevier Ltd. All rights reserved.
关键词Glycosmis Montana Rutaceae Diprenylated Indole Carbozole Anti-hiv C8166 Cytotoxicity Leukaemia
收录类别SCI ; IC
语种英语
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4720
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Yunnan 650204, Peoples R China
2.Chinese Acad Sci, Kunming Inst Zool, Kunming 650223, Peoples R China
3.German Canc Res Ctr, D-69120 Heidelberg, Germany
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Wang, JS,Zheng, YT,Efferth, T,et al. Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities[J]. PHYTOCHEMISTRY,2005,66(6):697-701.
APA Wang, JS,Zheng, YT,Efferth, T,Wang, RR,Shen, YM,&Hao, XJ.(2005).Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities.PHYTOCHEMISTRY,66(6),697-701.
MLA Wang, JS,et al."Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities".PHYTOCHEMISTRY 66.6(2005):697-701.
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