Pregnane alkaloids from Pachysandra axillaris
Sun, Yun1,2,3; Yan, Yu-Xin1,2; Chen, Jian-Chao1; Lu, Lu1,2; Zhang, Xian-Min1; Li, Yan1; Qiu, Ming-Hua1
2010-12-01
发表期刊STEROIDS
ISSN0039-128X
卷号75期号:12页码:818-824
摘要Nine new pregnane alkaloids, pachysamines J-R (1-9), together with seven known ones, were isolated from Pachysandra axillaris. The chemical structures of the new alkaloids were elucidated by spectroscopic methods. All the compounds were evaluated for their inhibitory activities against HL-60, SMMC-7721, A549, SK-BR-3, and PANC-1 cell lines. Compound 15 possessed moderate activities against A-549, SK-BR-3, and PANC-1 cells, with the IC(50) values of 11.17, 4.17, and 10.76 mu M, respectively. Besides, compound 11 showed cytotoxicities against A-549 cell, with the IC(50) values as 24.94 mu M. (C) 2010 Published by Elsevier Inc.
关键词Pregnane Alkaloids Pachysandra Axillaris Cytotoxic Activity
资助信息Foundation of Key State Lab. of Phytochemistry and Plant Resources in West China [P2008ZZ05]; CAS ; Chinese Academy of Sciences (CAS) [KSCX2-YW-G-038, KSCX2-YW-R-194, 29KZCX2-XB2-15-03]; National Natural Science Foundation of China [30772636]
学科领域Biochemistry & Molecular Biology ; Endocrinology & Metabolism
DOI10.1016/j.steroids.2010.05.005
收录类别SCI ; IC
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Endocrinology & Metabolism
WOS类目Biochemistry & Molecular Biology ; Endocrinology & Metabolism
WOS记录号WOS:000281932500004
引用统计
被引频次:13[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4664
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
3.Yunnan Univ Tradit Chinese Med, Kunming 650000, Yunnan, Peoples R China
推荐引用方式
GB/T 7714
Sun, Yun,Yan, Yu-Xin,Chen, Jian-Chao,et al. Pregnane alkaloids from Pachysandra axillaris[J]. STEROIDS,2010,75(12):818-824.
APA Sun, Yun.,Yan, Yu-Xin.,Chen, Jian-Chao.,Lu, Lu.,Zhang, Xian-Min.,...&Qiu, Ming-Hua.(2010).Pregnane alkaloids from Pachysandra axillaris.STEROIDS,75(12),818-824.
MLA Sun, Yun,et al."Pregnane alkaloids from Pachysandra axillaris".STEROIDS 75.12(2010):818-824.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
201202240025.pdf(298KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Sun, Yun]的文章
[Yan, Yu-Xin]的文章
[Chen, Jian-Chao]的文章
百度学术
百度学术中相似的文章
[Sun, Yun]的文章
[Yan, Yu-Xin]的文章
[Chen, Jian-Chao]的文章
必应学术
必应学术中相似的文章
[Sun, Yun]的文章
[Yan, Yu-Xin]的文章
[Chen, Jian-Chao]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。