Pseudoirroratin A, a new cytotoxic ent-kaurene diterpene from Isodon pseudo-irrorata

doi:10.1021/np010420h

	Pseudoirroratin A, a new cytotoxic ent-kaurene diterpene from Isodon pseudo-irrorata
	Zhang, HJ ; Fan, ZT ; Tan, GT ; Chai, HB ; Pezzuto, JM ; Sun, HD; Fong, HHS
通讯作者	Sun, HD, Acad Sinica, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
	2002-02-01
发表期刊	JOURNAL OF NATURAL PRODUCTS
ISSN	0163-3864
卷号	65 期号:2 页码:215-217
摘要	A new ent-kaurene diterpene, pseudoirroratin A (1), and a known diterpene, pseurata A, were isolated from Isodon pseudo-irrorata. Compound 1 showed significant cytotoxicity against the Lu1, SW626, LNCaP, KB, and HOS cancer cell, lines with IC50 values of 0.26 (0.75), 0.20 (0.57), 0.90 (2.59), 0.90 (2.59), and 0.50 (1.44) mug/mL (muM), respectively. The structure of 1 was elucidated by spectroscopic means including 1D and 2D NMR techniques.
学科领域	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI	10.1021/np010420h
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000174048900024
引用统计	被引频次：13[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/4582
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Acad Sinica, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China 2.Univ Illinois, Coll Pharm, Program Collaborat Res Pharmaceut Sci, Chicago, IL 60612 USA 3.Xizang Plateau Inst Biol, Lasa 850001, Peoples R China
推荐引用方式 GB/T 7714	Zhang, HJ,Fan, ZT,Tan, GT,et al. Pseudoirroratin A, a new cytotoxic ent-kaurene diterpene from Isodon pseudo-irrorata[J]. JOURNAL OF NATURAL PRODUCTS,2002,65(2):215-217.
APA	Zhang, HJ.,Fan, ZT.,Tan, GT.,Chai, HB.,Pezzuto, JM.,...&Fong, HHS.(2002).Pseudoirroratin A, a new cytotoxic ent-kaurene diterpene from Isodon pseudo-irrorata.JOURNAL OF NATURAL PRODUCTS,65(2),215-217.
MLA	Zhang, HJ,et al."Pseudoirroratin A, a new cytotoxic ent-kaurene diterpene from Isodon pseudo-irrorata".JOURNAL OF NATURAL PRODUCTS 65.2(2002):215-217.

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