| Phomopsterones A and B, Two Functionalized Ergostane-Type Steroids from the Endophytic Fungus Phomopsis sp TJ507A | |
| Hu, Zhengxi1; Wu, Ye1,2; Xie, Shuangshuang1; Sun, Weiguaug1; Guo, Yi1; Li, Xiao-Nian3; Liu, Junjun1; Li, Hua1; Wang, Jianping1; Luo, Zengwei1; Xue, Yongbo1; Zhang, Yonghui1 | |
| 2017-01-06 | |
| 发表期刊 | ORGANIC LETTERS
 |
| 卷号 | 19期号:1页码:258-261 |
| 摘要 | Two new functionalized ergostane-type steroids, phomopsterones A (1) and B (2), were isolated from the plant-derived Phomopsis sp. TJ507A. Their structures were determined on the basis of spectroscopic data, a modified Mosher's method, X-ray crystallographic analysis, and quantum chemical calculations. Compound 1 is an unprecedented ergosteroid featuring a, rearranged bicyclo[3.3.1]nonane motif resulting from B-ring scission and a subsequent 180 degrees rotation of the ring A during biosynthesis. Compound 2 exhibited anti-inflammatory activity. |
| DOI | 10.1021/acs.orglett.6b03557 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000391781600066 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/45636 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Huazhong Univ Sci & Technol, Tongji Med Coll, Hubei Key Lab Nat Med Chem & Resource Evaluat, Sch Pharm, Wuhan 430030, Peoples R China 2.Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Wuhan 430030, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hu, Zhengxi,Wu, Ye,Xie, Shuangshuang,et al. Phomopsterones A and B, Two Functionalized Ergostane-Type Steroids from the Endophytic Fungus Phomopsis sp TJ507A[J]. ORGANIC LETTERS,2017,19(1):258-261. |
| APA | Hu, Zhengxi.,Wu, Ye.,Xie, Shuangshuang.,Sun, Weiguaug.,Guo, Yi.,...&Zhang, Yonghui.(2017).Phomopsterones A and B, Two Functionalized Ergostane-Type Steroids from the Endophytic Fungus Phomopsis sp TJ507A.ORGANIC LETTERS,19(1),258-261. |
| MLA | Hu, Zhengxi,et al."Phomopsterones A and B, Two Functionalized Ergostane-Type Steroids from the Endophytic Fungus Phomopsis sp TJ507A".ORGANIC LETTERS 19.1(2017):258-261. |
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