Cytotoxic 7,20-epoxy ent-kauranoids from Isodon xerophilus

	Cytotoxic 7,20-epoxy ent-kauranoids from Isodon xerophilus
	Hou, AJ ; Zhao, QS; Li, ML ; Jiang, B ; Lin, ZW ; Sun, HD; Zhou, YP ; Lu, Y ; Zheng, QT
通讯作者	Sun, HD, Acad Sinica, Kunming Inst Bot, Lab Phytochem, Kunming 650204, Yunnan, Peoples R China
	2001-09-01
发表期刊	PHYTOCHEMISTRY
ISSN	0031-9422
卷号	58 期号:1 页码:179-183
摘要	Four 7.20-epoxy ent-kaurane diterpenoids. xerophilusins G (1) and I-K (2-4). were isolated from the leaves of Isodon xerophilus. along with four known ones, enanderianin C (5), rosthorin A (6), longikaurin B (7), and rabdoternin D (8). Their structures were determined primarily using NMR spectroscopic techniques. The structure and stereochemistry of 3 were confirmed by X-ray crystallography. Compounds 4 and 7 exhibited broad cytotoxicity against four kinds of human tumor cells (K562, HL-60, HCT, and MKN-28 cells) in the range of 2.23-15.35 and 0.30 8.61 mug/ml, respectively. (C) 2001 Elsevier Science Ltd. All rights reserved.
关键词	Isodon Xerophilus Labiatae Ent-kaurane Diterpenoids Xerophilusins g I-k
学科领域	Biochemistry & Molecular Biology ; Plant Sciences
收录类别	IC ; SCI
语种	英语
WOS记录号	WOS:000170464400022
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/4536
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Acad Sinica, Kunming Inst Bot, Lab Phytochem, Kunming 650204, Yunnan, Peoples R China 2.Kunming Med Coll, Yunnan Lab Pharmacol & Nat Prod, Kunming 650031, Yunnan, Peoples R China 3.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
推荐引用方式 GB/T 7714	Hou, AJ,Zhao, QS,Li, ML,et al. Cytotoxic 7,20-epoxy ent-kauranoids from Isodon xerophilus[J]. PHYTOCHEMISTRY,2001,58(1):179-183.
APA	Hou, AJ.,Zhao, QS.,Li, ML.,Jiang, B.,Lin, ZW.,...&Zheng, QT.(2001).Cytotoxic 7,20-epoxy ent-kauranoids from Isodon xerophilus.PHYTOCHEMISTRY,58(1),179-183.
MLA	Hou, AJ,et al."Cytotoxic 7,20-epoxy ent-kauranoids from Isodon xerophilus".PHYTOCHEMISTRY 58.1(2001):179-183.

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