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题名: Cytotoxic 7,20-epoxy ent-kauranoids from Isodon xerophilus
作者: Hou, AJ; null(赵勤实); Li, ML; Jiang, B; Lin, ZW; null(孙汉董); Zhou, YP; Lu, Y; Zheng, QT
刊名: PHYTOCHEMISTRY
关键词: Isodon xerophilus ; Labiatae ; ent-kaurane diterpenoids ; xerophilusins G, I-K
英文摘要: Four 7.20-epoxy ent-kaurane diterpenoids. xerophilusins G (1) and I-K (2-4). were isolated from the leaves of Isodon xerophilus. along with four known ones, enanderianin C (5), rosthorin A (6), longikaurin B (7), and rabdoternin D (8). Their structures were determined primarily using NMR spectroscopic techniques. The structure and stereochemistry of 3 were confirmed by X-ray crystallography. Compounds 4 and 7 exhibited broad cytotoxicity against four kinds of human tumor cells (K562, HL-60, HCT, and MKN-28 cells) in the range of 2.23-15.35 and 0.30 8.61 mug/ml, respectively. (C) 2001 Elsevier Science Ltd. All rights reserved.
出版日期: 2001-09-01
卷号: 58, 期号:1, 页码:179-183
语种: 英语
收录类别: IC ; SCI
学科分类: Biochemistry & Molecular Biology; Plant Sciences
ISSN号: 0031-9422
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/4536
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Acad Sinica, Kunming Inst Bot, Lab Phytochem, Kunming 650204, Yunnan, Peoples R China
2.Kunming Med Coll, Yunnan Lab Pharmacol & Nat Prod, Kunming 650031, Yunnan, Peoples R China
3.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China

Recommended Citation:
Hou, AJ; Zhao, QS; Li, ML; Jiang, B; Lin, ZW; Sun, HD; Zhou, YP; Lu, Y; Zheng, QT.Cytotoxic 7,20-epoxy ent-kauranoids from Isodon xerophilus,PHYTOCHEMISTRY,2001,58(1):179-183
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