Cytotoxic 7,20-epoxy ent-kauranoids from Isodon xerophilus
Hou, AJ; Zhao, QS; Li, ML; Jiang, B; Lin, ZW; Sun, HD; Zhou, YP; Lu, Y; Zheng, QT
2001-09-01
发表期刊PHYTOCHEMISTRY
ISSN0031-9422
卷号58期号:1页码:179-183
摘要Four 7.20-epoxy ent-kaurane diterpenoids. xerophilusins G (1) and I-K (2-4). were isolated from the leaves of Isodon xerophilus. along with four known ones, enanderianin C (5), rosthorin A (6), longikaurin B (7), and rabdoternin D (8). Their structures were determined primarily using NMR spectroscopic techniques. The structure and stereochemistry of 3 were confirmed by X-ray crystallography. Compounds 4 and 7 exhibited broad cytotoxicity against four kinds of human tumor cells (K562, HL-60, HCT, and MKN-28 cells) in the range of 2.23-15.35 and 0.30 8.61 mug/ml, respectively. (C) 2001 Elsevier Science Ltd. All rights reserved.
关键词Isodon Xerophilus Labiatae Ent-kaurane Diterpenoids Xerophilusins g I-k
学科领域Biochemistry & Molecular Biology ; Plant Sciences
收录类别IC ; SCI
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Plant Sciences
WOS类目Biochemistry & Molecular Biology ; Plant Sciences
WOS记录号WOS:000170464400022
引用统计
被引频次:29[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4536
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Acad Sinica, Kunming Inst Bot, Lab Phytochem, Kunming 650204, Yunnan, Peoples R China
2.Kunming Med Coll, Yunnan Lab Pharmacol & Nat Prod, Kunming 650031, Yunnan, Peoples R China
3.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
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Hou, AJ,Zhao, QS,Li, ML,et al. Cytotoxic 7,20-epoxy ent-kauranoids from Isodon xerophilus[J]. PHYTOCHEMISTRY,2001,58(1):179-183.
APA Hou, AJ.,Zhao, QS.,Li, ML.,Jiang, B.,Lin, ZW.,...&Zheng, QT.(2001).Cytotoxic 7,20-epoxy ent-kauranoids from Isodon xerophilus.PHYTOCHEMISTRY,58(1),179-183.
MLA Hou, AJ,et al."Cytotoxic 7,20-epoxy ent-kauranoids from Isodon xerophilus".PHYTOCHEMISTRY 58.1(2001):179-183.
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