| Vitexlactam A, a novel labdane diterpene lactam from the fruits of Vitex agnus-castus | |
Li, SH ; Zhang, HJ; Qiu, SX; Niu, XM; Santarsiero, BD; Mesecar, AD; Fong, HHS; Farnsworth, NR; Sun, HD
| |
| 2002-07-15 | |
| Source Publication | TETRAHEDRON LETTERS
 |
| ISSN | 0040-4039 |
| Volume | 43Issue:29Pages:5131-5134 |
| Abstract | A novel labdane diterpene alkaloid, vitexlactam A (1) was isolated as a prism from the n-hexane extract of the fruits of Vitex agnus-castus through normal and reverse phase column chromatography. Its structure was elucidated to be 6beta-acetoxy-9alpha-hydroxy-13(14)-labden-16,15-amide, based on chemical and spectral evidences including 1D and 2D NMR spectra. The structure was confirmed by X-ray crystallographic analysis. Compound 1 is the first naturally occurring labdane diterpenoid containing an alpha,beta-unsaturated gamma-lactam moiety. (C) 2002 Elsevier Science Ltd. All rights reserved. |
| Keyword | Vitex Agnus-castus Verbenaceae Labdane Diterpene Lactam Vitexlactam a Nmr X-ray |
| Subject Area | Chemistry, Organic |
| Indexed By | IC ; SCI |
| Language | 英语 |
| WOS ID | WOS:000176639100030 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/4330 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Affiliation | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Univ Illinois, Coll Pharm, Program Collaborat Res Pharmaceut Sci, Chicago, IL 60612 USA 3.Herbstandard Inc, Chesterfield, MO 63017 USA 4.Univ Illinois, Dept Med Chem & Pharmacognosy, Chicago, IL 60607 USA 5.Univ Illinois, Ctr Pharmaceut Biotechnol, Chicago, IL 60607 USA 6.Univ Illinois, UIC NIH Ctr Bot Dietary Supplements Res, Chicago, IL 60612 USA |
| Recommended Citation GB/T 7714 | Li, SH,Zhang, HJ,Qiu, SX,et al. Vitexlactam A, a novel labdane diterpene lactam from the fruits of Vitex agnus-castus[J]. TETRAHEDRON LETTERS,2002,43(29):5131-5134. |
| APA | Li, SH.,Zhang, HJ.,Qiu, SX.,Niu, XM.,Santarsiero, BD.,...&Sun, HD.(2002).Vitexlactam A, a novel labdane diterpene lactam from the fruits of Vitex agnus-castus.TETRAHEDRON LETTERS,43(29),5131-5134. |
| MLA | Li, SH,et al."Vitexlactam A, a novel labdane diterpene lactam from the fruits of Vitex agnus-castus".TETRAHEDRON LETTERS 43.29(2002):5131-5134. |
| Files in This Item: | Download All | |||||
| File Name/Size | DocType | Version | Access | License | ||
| 201201060014.pdf（145KB） | 开放获取 | -- | View Download | |||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment