Vitexlactam A, a novel labdane diterpene lactam from the fruits of Vitex agnus-castus

	Vitexlactam A, a novel labdane diterpene lactam from the fruits of Vitex agnus-castus
	Li, SH; Zhang, HJ ; Qiu, SX ; Niu, XM ; Santarsiero, BD ; Mesecar, AD ; Fong, HHS ; Farnsworth, NR ; Sun, HD
	2002-07-15
发表期刊	TETRAHEDRON LETTERS
ISSN	0040-4039
卷号	43 期号:29 页码:5131-5134
摘要	A novel labdane diterpene alkaloid, vitexlactam A (1) was isolated as a prism from the n-hexane extract of the fruits of Vitex agnus-castus through normal and reverse phase column chromatography. Its structure was elucidated to be 6beta-acetoxy-9alpha-hydroxy-13(14)-labden-16,15-amide, based on chemical and spectral evidences including 1D and 2D NMR spectra. The structure was confirmed by X-ray crystallographic analysis. Compound 1 is the first naturally occurring labdane diterpenoid containing an alpha,beta-unsaturated gamma-lactam moiety. (C) 2002 Elsevier Science Ltd. All rights reserved.
关键词	Vitex Agnus-castus Verbenaceae Labdane Diterpene Lactam Vitexlactam a Nmr X-ray
学科领域	Chemistry, Organic
收录类别	IC ; SCI
语种	英语
WOS记录号	WOS:000176639100030
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/4330
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Univ Illinois, Coll Pharm, Program Collaborat Res Pharmaceut Sci, Chicago, IL 60612 USA 3.Herbstandard Inc, Chesterfield, MO 63017 USA 4.Univ Illinois, Dept Med Chem & Pharmacognosy, Chicago, IL 60607 USA 5.Univ Illinois, Ctr Pharmaceut Biotechnol, Chicago, IL 60607 USA 6.Univ Illinois, UIC NIH Ctr Bot Dietary Supplements Res, Chicago, IL 60612 USA
推荐引用方式 GB/T 7714	Li, SH,Zhang, HJ,Qiu, SX,et al. Vitexlactam A, a novel labdane diterpene lactam from the fruits of Vitex agnus-castus[J]. TETRAHEDRON LETTERS,2002,43(29):5131-5134.
APA	Li, SH.,Zhang, HJ.,Qiu, SX.,Niu, XM.,Santarsiero, BD.,...&Sun, HD.(2002).Vitexlactam A, a novel labdane diterpene lactam from the fruits of Vitex agnus-castus.TETRAHEDRON LETTERS,43(29),5131-5134.
MLA	Li, SH,et al."Vitexlactam A, a novel labdane diterpene lactam from the fruits of Vitex agnus-castus".TETRAHEDRON LETTERS 43.29(2002):5131-5134.

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