Rubiyunnanins A and B, two novel cyclic hexapeptides from Rubia yunnanensis

doi:10.1016/j.tetlet.2010.07.066

	Rubiyunnanins A and B, two novel cyclic hexapeptides from Rubia yunnanensis
	Fan, Jun-Ting 1,2; Chen, Yi-Shan 1,2; Xu, Wen-Yan 1,2,3; Du, Liangcheng 3; Zeng, Guang-Zhi 1; Zhang, Yu-Mei 1; Su, Jia 1; Li, Yan1 ; Tan, Ning-Hua 1
	2010-12-29
发表期刊	TETRAHEDRON LETTERS
ISSN	0040-4039
卷号	51 期号:52 页码:6810-6813
摘要	Two novel cyclic hexapeptides, named rubiyunnanins A (1) and B (2), were isolated from the roots of Rubia yunnanensis (Franch.) Diels. Their structures were elucidated extensively by spectroscopic analysis and theoretical computation. Possible biosynthetic pathways for RAs, 1, and 2 were proposed. Compound 2 showed moderate cytotoxicities against 11 cancer cell lines and inhibited nitric oxide (NO) production in LPS and IFN-gamma-induced RAW 264.7 murine macrophages. (C) 2010 Elsevier Ltd. All rights reserved.
关键词	Rubia Yunnanensis Rubiyunnanin a Rubiyunnanin b Cyclopeptides Cytotoxicity Inhibition Of No Production
学科领域	Chemistry, Organic
DOI	10.1016/j.tetlet.2010.07.066
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000285670400004
引用统计	被引频次：46[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/4300
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Univ Nebraska, Dept Chem, Lincoln, NE 68588 USA
推荐引用方式 GB/T 7714	Fan, Jun-Ting,Chen, Yi-Shan,Xu, Wen-Yan,et al. Rubiyunnanins A and B, two novel cyclic hexapeptides from Rubia yunnanensis[J]. TETRAHEDRON LETTERS,2010,51(52):6810-6813.
APA	Fan, Jun-Ting.,Chen, Yi-Shan.,Xu, Wen-Yan.,Du, Liangcheng.,Zeng, Guang-Zhi.,...&Tan, Ning-Hua.(2010).Rubiyunnanins A and B, two novel cyclic hexapeptides from Rubia yunnanensis.TETRAHEDRON LETTERS,51(52),6810-6813.
MLA	Fan, Jun-Ting,et al."Rubiyunnanins A and B, two novel cyclic hexapeptides from Rubia yunnanensis".TETRAHEDRON LETTERS 51.52(2010):6810-6813.

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