Acortatarins A and B, Two Novel Antioxidative Spiroalkaloids with a Naturally Unusual Morpholine Motif from Acorus tatarinowii

doi:10.1021/ol100451p

	Acortatarins A and B, Two Novel Antioxidative Spiroalkaloids with a Naturally Unusual Morpholine Motif from Acorus tatarinowii
	Tong, Xiao-Gang 2,3; Zhou, Li-Li 1; Wang, Yue-Hu2 ; Xia, Chengfeng 2; Wang, Ye 4,5; Liang, Min ; Hou, Fan-Fan 1; Cheng, Yong-Xian 2
	2010-04-16
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	12 期号:8 页码:1844-1847
摘要	Acortatarins A (1) and B (2), two novel spiroalkaloids with a naturally unusual morpholine motif, were isolated from the rhizome of Acorus tatarinowii. Their structures with absolute configuration were determined by spectroscopic methods, X-ray diffraction analysis, and Masher's method. Importantly, compound 1 could significantly inhibit reactive oxygen species production in high-glucose-stimulated mesangial cells in a dose- and time-dependent manner.
关键词	High-glucose Mesangial Cells Expression Inhibitors Activation Products Oxidase Acid
学科领域	Chemistry, Organic
DOI	10.1021/ol100451p
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000276562600050
引用统计	被引频次：81[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/4282
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.So Med Univ, Div Nephrol, Nanfang Hosp, Key Lab Organ Failure Res,Educ Minist, Guangzhou 510515, Guangdong, Peoples R China 2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 4.Chinese Acad Sci, Guiyang 550002, Guizhou, Peoples R China 5.Key Lab Chem Nat Prod Guizhou Prov, Guiyang 550002, Guizhou, Peoples R China
推荐引用方式 GB/T 7714	Tong, Xiao-Gang,Zhou, Li-Li,Wang, Yue-Hu,et al. Acortatarins A and B, Two Novel Antioxidative Spiroalkaloids with a Naturally Unusual Morpholine Motif from Acorus tatarinowii[J]. ORGANIC LETTERS,2010,12(8):1844-1847.
APA	Tong, Xiao-Gang.,Zhou, Li-Li.,Wang, Yue-Hu.,Xia, Chengfeng.,Wang, Ye.,...&Cheng, Yong-Xian.(2010).Acortatarins A and B, Two Novel Antioxidative Spiroalkaloids with a Naturally Unusual Morpholine Motif from Acorus tatarinowii.ORGANIC LETTERS,12(8),1844-1847.
MLA	Tong, Xiao-Gang,et al."Acortatarins A and B, Two Novel Antioxidative Spiroalkaloids with a Naturally Unusual Morpholine Motif from Acorus tatarinowii".ORGANIC LETTERS 12.8(2010):1844-1847.

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