Novel Cyclic Hexapeptides from Marine-Derived Fungus, Aspergillus sclerotiorum PT06-1

doi:10.1021/ol902197z

	Novel Cyclic Hexapeptides from Marine-Derived Fungus, Aspergillus sclerotiorum PT06-1
	Zheng, Jinkai 1; Zhu, Huajie 2; Hong, Kui 3; Wang, Yi 1; Liu, Peipei 1; Wang, Xin 1; Peng, Xiaoping 1; Zhu, Weiming 1
	2009-11-19
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	11 期号:22 页码:5262-5265
摘要	Two novel cyclic hexapeptides containing both anthranilic acid and dehydroamino acid units, sclerotides A (1) and B (2), were isolated from the marine-derived halotolerant Aspergillus sclerotiorum PT06-1 in a nutrient-limited hypersaline medium. Both 1 and 2 are photointerconvertible and could be interconverted via a radical reaction Initiated by direct photoisomerization. Both compounds showed moderate antifungal activity. Compound 2 also showed weak cytotoxicity and antibacterial activity.
关键词	Alkaloids Cyclopeptides Assay
学科领域	Chemistry, Organic
DOI	10.1021/ol902197z
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000271583000043
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/4272
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Ocean Univ China, Key Lab Marine Drugs, Chinese Minist Educ, Sch Med & Pharm, Qingdao 266003, Peoples R China 2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources, Kunming Inst Bot, Kunming 650204, Peoples R China 3.Chinese Acad Trop Agr Sci, Inst Trop Biol Sci & Biotechnol, Haikou 571101, Peoples R China
推荐引用方式 GB/T 7714	Zheng, Jinkai,Zhu, Huajie,Hong, Kui,et al. Novel Cyclic Hexapeptides from Marine-Derived Fungus, Aspergillus sclerotiorum PT06-1[J]. ORGANIC LETTERS,2009,11(22):5262-5265.
APA	Zheng, Jinkai.,Zhu, Huajie.,Hong, Kui.,Wang, Yi.,Liu, Peipei.,...&Zhu, Weiming.(2009).Novel Cyclic Hexapeptides from Marine-Derived Fungus, Aspergillus sclerotiorum PT06-1.ORGANIC LETTERS,11(22),5262-5265.
MLA	Zheng, Jinkai,et al."Novel Cyclic Hexapeptides from Marine-Derived Fungus, Aspergillus sclerotiorum PT06-1".ORGANIC LETTERS 11.22(2009):5262-5265.

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