Novel Cyclic Hexapeptides from Marine-Derived Fungus, Aspergillus sclerotiorum PT06-1
Zheng, Jinkai1; Zhu, Huajie2; Hong, Kui3; Wang, Yi1; Liu, Peipei1; Wang, Xin1; Peng, Xiaoping1; Zhu, Weiming1
2009-11-19
发表期刊ORGANIC LETTERS
ISSN1523-7060
卷号11期号:22页码:5262-5265
摘要Two novel cyclic hexapeptides containing both anthranilic acid and dehydroamino acid units, sclerotides A (1) and B (2), were isolated from the marine-derived halotolerant Aspergillus sclerotiorum PT06-1 in a nutrient-limited hypersaline medium. Both 1 and 2 are photointerconvertible and could be interconverted via a radical reaction Initiated by direct photoisomerization. Both compounds showed moderate antifungal activity. Compound 2 also showed weak cytotoxicity and antibacterial activity.
关键词Alkaloids Cyclopeptides Assay
资助信息National Natural Science Foundation of China [30470196, 30670219]; Project of Chinese National Programs for High Technology Research and Development [2007AA091502]
学科领域Chemistry, Organic
DOI10.1021/ol902197z
收录类别SCI ; IC
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Organic
WOS记录号WOS:000271583000043
引用统计
被引频次:49[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4272
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Ocean Univ China, Key Lab Marine Drugs, Chinese Minist Educ, Sch Med & Pharm, Qingdao 266003, Peoples R China
2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources, Kunming Inst Bot, Kunming 650204, Peoples R China
3.Chinese Acad Trop Agr Sci, Inst Trop Biol Sci & Biotechnol, Haikou 571101, Peoples R China
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GB/T 7714
Zheng, Jinkai,Zhu, Huajie,Hong, Kui,et al. Novel Cyclic Hexapeptides from Marine-Derived Fungus, Aspergillus sclerotiorum PT06-1[J]. ORGANIC LETTERS,2009,11(22):5262-5265.
APA Zheng, Jinkai.,Zhu, Huajie.,Hong, Kui.,Wang, Yi.,Liu, Peipei.,...&Zhu, Weiming.(2009).Novel Cyclic Hexapeptides from Marine-Derived Fungus, Aspergillus sclerotiorum PT06-1.ORGANIC LETTERS,11(22),5262-5265.
MLA Zheng, Jinkai,et al."Novel Cyclic Hexapeptides from Marine-Derived Fungus, Aspergillus sclerotiorum PT06-1".ORGANIC LETTERS 11.22(2009):5262-5265.
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