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题名: Lancifodilactone G: A unique nortriterpenoid isolated from Schisandra lancifolia and its anti-HIV activity
作者: Xiao, WL; Zhu, HJ; Shen, YH; Li, RT; null(黎胜红); null(孙汉董); Zheng, YT; Wang, RR; Lu, Y; Wang, C; Zheng, QT
刊名: ORGANIC LETTERS
英文摘要: Lancifodilactone G (1), a novel, highly oxygenated nortriterpenoid featuring a partial enol structure and a spirocyclic moiety, was isolated from the medicinal plant Schisandra lancifolia. Its structure and stereochemistry were determined from extensive one- and two-dimensional NMR and mass spectral data, coupled with single-crystal X-ray analysis. Compound 1 exerted minimal cytotoxicity against C8166 cells (CC50 > 200 mu g/mL) and showed anti-HIV activity with EC50 = 95.47 +/- 14.19 mu g/mL and a selectivity index in the range of 1.82-2.46.
出版日期: 2005-05-26
卷号: 7, 期号:11, 页码:2145-2148
DOI标识: 10.1021/ol050502n
语种: 英语
ISSN号: 1523-7060
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/4260
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
2.Chinese Acad Sci, Kunming Inst Zool, Lab Mol Immunopharmacol, Kunming 650223, Peoples R China
3.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
4.Chinese Acad Sci, Grad Sch, Beijing 10039, Peoples R China

Recommended Citation:
Xiao, WL; Zhu, HJ; Shen, YH; Li, RT; Li, SH; Sun, HD; Zheng, YT; Wang, RR; Lu, Y; Wang, C; Zheng, QT.Lancifodilactone G: A unique nortriterpenoid isolated from Schisandra lancifolia and its anti-HIV activity,ORGANIC LETTERS,2005,7(11):2145-2148
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