Lancifodilactone F: A novel nortriterpenoid possessing a unique skeleton from Schisandra lancifolia and its anti-HIV activity

doi:10.1021/ol0473187

	Lancifodilactone F: A novel nortriterpenoid possessing a unique skeleton from Schisandra lancifolia and its anti-HIV activity
	Xiao, WL ; Li, RT ; Li, SH; Li, XL ; Sun, HD; Zheng, YT ; Wang, RR ; Lu, Y ; Wang, C; Zheng, QT
	2005-03-31
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	7 期号:7 页码:1263-1266
摘要	Lancifodilactone F (1), possessing an unprecedented rearranged pentanortriterpenoid backbone derived from cycloartane, was isolated from the leaves and stems of Schisandra lancifolia (Rehd. et Wils) A. C. Smith. Its structure was established by comprehensive NMR and MS spectroscopic analysis, coupled with single-crystal X-ray experiment. Compound 1 exerted minimal cytotoxicity against C8166 cells (CC50 > 200 mu g/mL) and showed anti-HIV activity with EC50 = 20.69 +/- 3.31 mu g/mL and a selectivity index > 6.62.
学科领域	Chemistry, Organic
DOI	10.1021/ol0473187
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000227921200017
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/4258
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Chinese Acad Sci, Lab Mol Immunopharmacol, Kunming Inst Zool, Kunming 650223, Yunan, Peoples R China 3.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China 4.Chinese Acad Sci, Grad Sch, Beijing 10039, Peoples R China
推荐引用方式 GB/T 7714	Xiao, WL,Li, RT,Li, SH,et al. Lancifodilactone F: A novel nortriterpenoid possessing a unique skeleton from Schisandra lancifolia and its anti-HIV activity[J]. ORGANIC LETTERS,2005,7(7):1263-1266.
APA	Xiao, WL.,Li, RT.,Li, SH.,Li, XL.,Sun, HD.,...&Zheng, QT.(2005).Lancifodilactone F: A novel nortriterpenoid possessing a unique skeleton from Schisandra lancifolia and its anti-HIV activity.ORGANIC LETTERS,7(7),1263-1266.
MLA	Xiao, WL,et al."Lancifodilactone F: A novel nortriterpenoid possessing a unique skeleton from Schisandra lancifolia and its anti-HIV activity".ORGANIC LETTERS 7.7(2005):1263-1266.

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