Coriatone and corianlactone, two novel sesquiterpenes from Coriaria nepalensis | |
Shen, YH; Li, SH; Li, RT; Han, QB; Zhao, QS; Liang, L; Sun, HD; Lu, Y; Cao, P; Zheng, QT | |
2004-05-13 | |
发表期刊 | ORGANIC LETTERS |
ISSN | 1523-7060 |
卷号 | 6期号:10页码:1593-1595 |
摘要 | Both coriatone (1), a novel highly oxygenated picrotoxane-type sesquiterpene, and corianlactone (2), with an unprecedented sesquiterpene basic skeleton, named coriane, were isolated from Coriaria nepalensis Wall. The structures of 1 and 2 were determined by analysis of their two-dimensional NMR data, and the structure of 2 was confirmed by X-ray analysis. Compounds 1 and 2 showed no remarkable inhibitory activity toward K-562 cells. They are cytotoxic with IC50 > 50 mug/mL (cis-platinim: IC50 = 0.49 mug/mL). |
学科领域 | Chemistry, Organic |
DOI | 10.1021/ol049660p |
收录类别 | SCI ; IC |
语种 | 英语 |
WOS记录号 | WOS:000221278500019 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/4254 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China |
推荐引用方式 GB/T 7714 | Shen, YH,Li, SH,Li, RT,et al. Coriatone and corianlactone, two novel sesquiterpenes from Coriaria nepalensis[J]. ORGANIC LETTERS,2004,6(10):1593-1595. |
APA | Shen, YH.,Li, SH.,Li, RT.,Han, QB.,Zhao, QS.,...&Zheng, QT.(2004).Coriatone and corianlactone, two novel sesquiterpenes from Coriaria nepalensis.ORGANIC LETTERS,6(10),1593-1595. |
MLA | Shen, YH,et al."Coriatone and corianlactone, two novel sesquiterpenes from Coriaria nepalensis".ORGANIC LETTERS 6.10(2004):1593-1595. |
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