Coriatone and corianlactone, two novel sesquiterpenes from Coriaria nepalensis

doi:10.1021/ol049660p

	Coriatone and corianlactone, two novel sesquiterpenes from Coriaria nepalensis
	Shen, YH ; Li, SH; Li, RT ; Han, QB ; Zhao, QS; Liang, L ; Sun, HD; Lu, Y ; Cao, P ; Zheng, QT
	2004-05-13
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	6 期号:10 页码:1593-1595
摘要	Both coriatone (1), a novel highly oxygenated picrotoxane-type sesquiterpene, and corianlactone (2), with an unprecedented sesquiterpene basic skeleton, named coriane, were isolated from Coriaria nepalensis Wall. The structures of 1 and 2 were determined by analysis of their two-dimensional NMR data, and the structure of 2 was confirmed by X-ray analysis. Compounds 1 and 2 showed no remarkable inhibitory activity toward K-562 cells. They are cytotoxic with IC50 > 50 mug/mL (cis-platinim: IC50 = 0.49 mug/mL).
学科领域	Chemistry, Organic
DOI	10.1021/ol049660p
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000221278500019
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/4254
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
推荐引用方式 GB/T 7714	Shen, YH,Li, SH,Li, RT,et al. Coriatone and corianlactone, two novel sesquiterpenes from Coriaria nepalensis[J]. ORGANIC LETTERS,2004,6(10):1593-1595.
APA	Shen, YH.,Li, SH.,Li, RT.,Han, QB.,Zhao, QS.,...&Zheng, QT.(2004).Coriatone and corianlactone, two novel sesquiterpenes from Coriaria nepalensis.ORGANIC LETTERS,6(10),1593-1595.
MLA	Shen, YH,et al."Coriatone and corianlactone, two novel sesquiterpenes from Coriaria nepalensis".ORGANIC LETTERS 6.10(2004):1593-1595.

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