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题名: Dibenzocyclooctadiene Lignans from Schisandra wilsoniana and Their Anti-HIV-1 Activities
作者: Guang-Yu Yang; Yin-Ke Li; Rui-Rui Wang; Xiao-Nian Li; Wei-Lie Xiao; Liu-Meng Yang; Jian-Xin Pu; Yong-Tang Zheng; Han-Dong Sun
刊名: JOURNAL OF NATURAL PRODUCTS
关键词: SCHIZANDRA-CHINENSIS BAILL ; ANTI-HIV ACTIVITY ; KADSURA-LONGIPEDUNCULATA ; ABSOLUTE STRUCTURE ; GOMISIN-G ; CONSTITUENTS ; INTERIOR ; FRUITS
英文摘要: Twelve new dibenzocyclooctadiene lignans, marlignans A-L (1-12), together with 16 known compounds, were isolated from the leaves and stems of Schisandra wilsoniana. The structures of 1-12 were elucidated by spectroscopic methods including 1D- and 2D-NMR techniques. Compounds 1-12 were evaluated for their anti-HIV activities, of which compounds 3, 6, 8, and 12 showed modest activities with therapeutic index values of 13.2, 15.6, 17.6, and 16.4, respectively.
出版日期: 2010-05-01
卷号: 73, 期号:5, 页码:915-919
语种: 英语
收录类别: SCI ; IC
学科分类: Plant Sciences; Chemistry, Medicinal; Pharmacology & Pharmacy
ISSN号: 0163-3864
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/4230
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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Recommended Citation:
Yang, GY; Li, YK; Wang, RR; Li, XN; Xiao, WL; Yang, LM; Pu, JX; Zheng, YT; Sun, HD.Dibenzocyclooctadiene Lignans from Schisandra wilsoniana and Their Anti-HIV-1 Activities,JOURNAL OF NATURAL PRODUCTS,2010,73(5):915-919
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