Antibacterial activities of neolignans isolated from the seed endotheliums of Trewia nudiflora

	Antibacterial activities of neolignans isolated from the seed endotheliums of Trewia nudiflora
	Li, GH ; Zhao, PJ ; Shen, YM ; Zhang, KQ
	2004-09-01
发表期刊	ACTA BOTANICA SINICA
ISSN	1672-6650
卷号	46 期号:9 页码:1122-1127
摘要	Five neolignans including four new ones were obtained from the seed endotheliums of Trewia nudiflora L. Their structures were determined to be 9'-methyl americanol A (1), 9'-methyl isoamericanol A (2), 9'-ethyl americanol A (3), 9'-butyl americanol A (4), and americanin (5). Two acetylated products 3,4diacetyl americanin (5a) and 3,4,9-triacetyl americanin (5b) had been prepared from compound 5. All of these compounds were investigated on antibacterial assays when carbenicillin sodium, streptomycin sulfate and rifampicin were used as positive controls. Compounds 4 and 5 exhibited antibacterial activities against gram-positive bacterium Staphylococcus aureus and gram-negative bacterium Mycobacteriurn tuberculosis at the minimum inhibitory concentrations (MIC) of 50 mug/mL and 100 mug/mL, respectively, but 5a and 5b did not exhibit antibacterial activity at 200 mug/disk.
关键词	Trewia Nudiflora Seed Endothelium Neolignan Antibacterial Activity
学科领域	Biochemistry & Molecular Biology ; Plant Sciences
收录类别	SCI
语种	英语
WOS记录号	WOS:000224034800016
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/4220
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Yunnan Univ, Lab Conservat & Utilizat Bio Resource, Kunming 650091, Peoples R China
推荐引用方式 GB/T 7714	Li, GH,Zhao, PJ,Shen, YM,et al. Antibacterial activities of neolignans isolated from the seed endotheliums of Trewia nudiflora[J]. ACTA BOTANICA SINICA,2004,46(9):1122-1127.
APA	Li, GH,Zhao, PJ,Shen, YM,&Zhang, KQ.(2004).Antibacterial activities of neolignans isolated from the seed endotheliums of Trewia nudiflora.ACTA BOTANICA SINICA,46(9),1122-1127.
MLA	Li, GH,et al."Antibacterial activities of neolignans isolated from the seed endotheliums of Trewia nudiflora".ACTA BOTANICA SINICA 46.9(2004):1122-1127.

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