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题名: Antibacterial activities of neolignans isolated from the seed endotheliums of Trewia nudiflora
作者: Li, GH; Zhao, PJ; Shen, YM; Zhang, KQ
刊名: ACTA BOTANICA SINICA
关键词: Trewia nudiflora ; seed endothelium ; neolignan ; antibacterial activity
英文摘要: Five neolignans including four new ones were obtained from the seed endotheliums of Trewia nudiflora L. Their structures were determined to be 9'-methyl americanol A (1), 9'-methyl isoamericanol A (2), 9'-ethyl americanol A (3), 9'-butyl americanol A (4), and americanin (5). Two acetylated products 3,4diacetyl americanin (5a) and 3,4,9-triacetyl americanin (5b) had been prepared from compound 5. All of these compounds were investigated on antibacterial assays when carbenicillin sodium, streptomycin sulfate and rifampicin were used as positive controls. Compounds 4 and 5 exhibited antibacterial activities against gram-positive bacterium Staphylococcus aureus and gram-negative bacterium Mycobacteriurn tuberculosis at the minimum inhibitory concentrations (MIC) of 50 mug/mL and 100 mug/mL, respectively, but 5a and 5b did not exhibit antibacterial activity at 200 mug/disk.
出版日期: 2004-09-01
卷号: 46, 期号:9, 页码:1122-1127
语种: 英语
ISSN号: 1672-6650
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/4220
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Yunnan Univ, Lab Conservat & Utilizat Bio Resource, Kunming 650091, Peoples R China

Recommended Citation:
Li, GH; Zhao, PJ; Shen, YM; Zhang, KQ.Antibacterial activities of neolignans isolated from the seed endotheliums of Trewia nudiflora,ACTA BOTANICA SINICA,2004,46(9):1122-1127
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