Triterpenoid Alkaloids from Buxus microphylla

	Triterpenoid Alkaloids from Buxus microphylla
	Yan, Yu-Xin 1,2; Chen, Jian-Chao 1; Sun, Yun 1,2; Wang, Yuan-Yuan 1; Su, Jia 1; Li, Yan1 ; Qiu, Ming-Hua1
	2010
发表期刊	CHEMISTRY & BIODIVERSITY
ISSN	1612-1872
卷号	7 期号:7 页码:1822-1827
摘要	Two new triterpenoid alkaloids, buxmicrophyllines J and K (1 and 2, resp.), together with four analogues, 3-6, were isolated from the leaves and stems of Buxus microphylla. The structures of the new compounds were elucidated by NMR and MS spectroscopic analyses. The partial assignments of the NMR spectra of 3 were also revised. Compounds 1 and 3-6 were evaluated for their growth inhibitory activity against human cell lines HL-60, SMMC-7721, A-549, SK-BR-3, and PANC-1. Compound 6 showed significant cytotoxicity against HL-60). SK-BR-3, and PANC-1 cell lines, with IC(50) values of 6.46, 19.61, and 28.57 mu m, respectively.
关键词	Cycloeucalenol Interrelation Configuration Cyclobuxine Hyrcana
学科领域	Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
收录类别	SCI
语种	英语
WOS记录号	WOS:000280613000015
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/4062
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Yan, Yu-Xin,Chen, Jian-Chao,Sun, Yun,et al. Triterpenoid Alkaloids from Buxus microphylla[J]. CHEMISTRY & BIODIVERSITY,2010,7(7):1822-1827.
APA	Yan, Yu-Xin.,Chen, Jian-Chao.,Sun, Yun.,Wang, Yuan-Yuan.,Su, Jia.,...&Qiu, Ming-Hua.(2010).Triterpenoid Alkaloids from Buxus microphylla.CHEMISTRY & BIODIVERSITY,7(7),1822-1827.
MLA	Yan, Yu-Xin,et al."Triterpenoid Alkaloids from Buxus microphylla".CHEMISTRY & BIODIVERSITY 7.7(2010):1822-1827.

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