Triterpenoid Alkaloids from Buxus microphylla
Yan, Yu-Xin1,2; Chen, Jian-Chao1; Sun, Yun1,2; Wang, Yuan-Yuan1; Su, Jia1; Li, Yan1; Qiu, Ming-Hua1
2010
发表期刊CHEMISTRY & BIODIVERSITY
ISSN1612-1872
卷号7期号:7页码:1822-1827
摘要Two new triterpenoid alkaloids, buxmicrophyllines J and K (1 and 2, resp.), together with four analogues, 3-6, were isolated from the leaves and stems of Buxus microphylla. The structures of the new compounds were elucidated by NMR and MS spectroscopic analyses. The partial assignments of the NMR spectra of 3 were also revised. Compounds 1 and 3-6 were evaluated for their growth inhibitory activity against human cell lines HL-60, SMMC-7721, A-549, SK-BR-3, and PANC-1. Compound 6 showed significant cytotoxicity against HL-60). SK-BR-3, and PANC-1 cell lines, with IC(50) values of 6.46, 19.61, and 28.57 mu m, respectively.
关键词Cycloeucalenol Interrelation Configuration Cyclobuxine Hyrcana
学科领域Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
收录类别SCI
语种英语
WOS记录号WOS:000280613000015
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4062
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
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GB/T 7714
Yan, Yu-Xin,Chen, Jian-Chao,Sun, Yun,et al. Triterpenoid Alkaloids from Buxus microphylla[J]. CHEMISTRY & BIODIVERSITY,2010,7(7):1822-1827.
APA Yan, Yu-Xin.,Chen, Jian-Chao.,Sun, Yun.,Wang, Yuan-Yuan.,Su, Jia.,...&Qiu, Ming-Hua.(2010).Triterpenoid Alkaloids from Buxus microphylla.CHEMISTRY & BIODIVERSITY,7(7),1822-1827.
MLA Yan, Yu-Xin,et al."Triterpenoid Alkaloids from Buxus microphylla".CHEMISTRY & BIODIVERSITY 7.7(2010):1822-1827.
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