A new cytotoxic cardenolide from the latex of Antiaris toxicaria
Gan, Yu Juan1; Mei, Wen Li1; Zhao, You Xing2; Dai, Hao Fu1
2009-04-01
发表期刊CHINESE CHEMICAL LETTERS
ISSN1001-8417
卷号20期号:4页码:450-452
摘要A new cardenolide, toxicarioside E (1), was isolated from the latex of Antiaris toxicaria (Pers.) Lesch (Moraceac). Its structure was elucidated on the basis of spectral data and chemical evidence. Compound 1 showed significant cytotoxicity against K562 and SGC-7901 cell lines in vitro by MTT method with the IC(50) value of 0.026 and 0.027 mu g/mL, respectively. (C) 2008 Hao Fu Dai. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
关键词Antiaris Toxicaria Moraceae Toxicarioside e Cardenolide Cytotoxicity
资助信息National Natural Science Foundation of China [30860345]; National Basic Research Program of China [2007CB116306]; National Nonprofit Institute Research Grant of CATAS-ITBB [ITBBZD200744]; Natural Science Foundation of Hainan [80671, 30608]
收录类别SCI
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4030
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
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GB/T 7714
Gan, Yu Juan,Mei, Wen Li,Zhao, You Xing,et al. A new cytotoxic cardenolide from the latex of Antiaris toxicaria[J]. CHINESE CHEMICAL LETTERS,2009,20(4):450-452.
APA Gan, Yu Juan,Mei, Wen Li,Zhao, You Xing,&Dai, Hao Fu.(2009).A new cytotoxic cardenolide from the latex of Antiaris toxicaria.CHINESE CHEMICAL LETTERS,20(4),450-452.
MLA Gan, Yu Juan,et al."A new cytotoxic cardenolide from the latex of Antiaris toxicaria".CHINESE CHEMICAL LETTERS 20.4(2009):450-452.
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