Diterpenoids of the Cassane Type from Caesalpinia decapetala
Qiao, Yuben1,2; Xu, Qianqian1,2; Hu, Zhengxi1,2; Li, Xiao-Nian3; Xiang, Ming1,2; Liu, Junjun1,2; Huang, Jinfeng1,2; Zhu, Hucheng1,2; Wang, Jianping1,2; Luo, Zengwei1,2; Xue, Yongbo1,2; Zhang, Yonghui1,2
2016-12-01
发表期刊JOURNAL OF NATURAL PRODUCTS
卷号79期号:12页码:3134-3142
摘要Eighteen compounds, including eight new cassane-type furanoditerpenoids, 3 beta-hydroxyphanginin H (1), 3 beta-acetoxyphanginin H (2), 7 beta-acetoxyphanginin H (3), 7,beta-hydroxyphanginin 1-1 (4), 4-epi-3,6-hydroxycaesalpinilinn (5), 4-epi-3 beta-acetoxycaesalpinilinn (6), 20-acetoxytaepeenin D (7), and tomocin E (8), along with 10 known compounds (9-18) were isolated from the roots of Caesalpinia decapetala. Compounds 1-13 were isolated from C. decapetala for the first time. The new compounds with their absolute configurations were determined by extensive spectroscopic analysis, single-crystal X-ray diffraction, and electronic circular dichroism calculations. Compounds 1, 4, 5, 7, and 11 exhibited inhibitory activities against the SW1990 human pancreatic cancer cell line with IC50 values ranging from 2.9 to 8.9 mu M.
DOI10.1021/acs.jnatprod.6b00910
收录类别SCI
语种英语
WOS记录号WOS:000390832700019
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/33791
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Huazhong Univ Sci & Technol, Hubei Key Lab Nat Med Chem & Resource Evaluat, Wuhan 430030, Hubei Province, Peoples R China
2.Huazhong Univ Sci & Technol, Dept Pharmacol, Sch Pharm, Tongji Med Coll, Wuhan 430030, Hubei Province, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China
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Qiao, Yuben,Xu, Qianqian,Hu, Zhengxi,et al. Diterpenoids of the Cassane Type from Caesalpinia decapetala[J]. JOURNAL OF NATURAL PRODUCTS,2016,79(12):3134-3142.
APA Qiao, Yuben.,Xu, Qianqian.,Hu, Zhengxi.,Li, Xiao-Nian.,Xiang, Ming.,...&Zhang, Yonghui.(2016).Diterpenoids of the Cassane Type from Caesalpinia decapetala.JOURNAL OF NATURAL PRODUCTS,79(12),3134-3142.
MLA Qiao, Yuben,et al."Diterpenoids of the Cassane Type from Caesalpinia decapetala".JOURNAL OF NATURAL PRODUCTS 79.12(2016):3134-3142.
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