| Cochlearoids F-K: Phenolic meroterpenoids from the fungus Ganoderma cochlear and their renoprotective activity | |
| Wang, Xin-Long1,2; Zhou, Feng-Jiao2,3; Dou, Man2; Yan, Yong-Ming2; Wang, Shu-Mei3; Di, Lei2; Cheng, Yong-Xian1,2 | |
| 2016-11-15 | |
| 发表期刊 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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| 卷号 | 26期号:22页码:5507-5512 |
| 摘要 | Ganoderma mushrooms are of great nutritious and medicinal values. This study was designed to characterize compounds from the fruiting bodies of Ganoderma cochlear and investigate their protective effects against kidney disorders. Six novel meroterpenoids cochlearoids F-K (1-6) were isolated by utilizing phytochemical approaches. Their structures were identified on the basis of extensive spectroscopic data and calculation methods. Biological evaluation shows that compounds 1-4 and 6 exhibit potent inhibitory activity on fibronectin overproduction in TGF-beta 1-induced HKC-8 cells. (C) 2016 Elsevier Ltd. All rights reserved. |
| 关键词 | Ganoderma Cochlear Meroterpenoids C-13 Nmr Calculations Renoprotection |
| DOI | 10.1016/j.bmcl.2016.10.011 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000388251400024 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/33673 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Henan Univ Chinese Med, Zhengzhou 450008, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 3.Guangdong Pharmaceut Univ, Guangzhou 510006, Guangdong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Xin-Long,Zhou, Feng-Jiao,Dou, Man,et al. Cochlearoids F-K: Phenolic meroterpenoids from the fungus Ganoderma cochlear and their renoprotective activity[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2016,26(22):5507-5512. |
| APA | Wang, Xin-Long.,Zhou, Feng-Jiao.,Dou, Man.,Yan, Yong-Ming.,Wang, Shu-Mei.,...&Cheng, Yong-Xian.(2016).Cochlearoids F-K: Phenolic meroterpenoids from the fungus Ganoderma cochlear and their renoprotective activity.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,26(22),5507-5512. |
| MLA | Wang, Xin-Long,et al."Cochlearoids F-K: Phenolic meroterpenoids from the fungus Ganoderma cochlear and their renoprotective activity".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 26.22(2016):5507-5512. |
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