Two new secoiridoids and other anti-hepatitis B virus active constituents from Swertia patens

doi:10.1080/10286020.2015.1116523

	Two new secoiridoids and other anti-hepatitis B virus active constituents from Swertia patens
	He, Kang; Geng, Chang-An; Cao, Tuan-Wu; Wang, Hong-Ling; Ma, Yun-Bao; Zhang, Xue-Mei; Chen, Ji-Jun
	2016
发表期刊	JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
卷号	18 期号:6 页码:528-534
摘要	Two new secoiridoids, swerpatic acid (1) with an unusual C-8 skeleton and swerpalactone (2), were isolated along with ten known compounds (3-12) from the whole plants of Swertia patens. Their structures were elucidated by comprehensive spectroscopic analyses. Eight compounds were evaluated for their anti-hepatitis B virus (HBV) activities on Hep G 2.2.15 cell line in vitro. Compounds 4 and 10 showed moderate inhibitory activities on the secretion of HBsAg with IC50 values of 1.96 and 0.50 mM.
关键词	Swertia Patens Secoiridoids Swerpatic Acid Swerpalactone Anti-hbv Activity
DOI	10.1080/10286020.2015.1116523
收录类别	SCI
语种	英语
WOS记录号	WOS:000379666400003
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/28476
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
推荐引用方式 GB/T 7714	He, Kang,Geng, Chang-An,Cao, Tuan-Wu,et al. Two new secoiridoids and other anti-hepatitis B virus active constituents from Swertia patens[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2016,18(6):528-534.
APA	He, Kang.,Geng, Chang-An.,Cao, Tuan-Wu.,Wang, Hong-Ling.,Ma, Yun-Bao.,...&Chen, Ji-Jun.(2016).Two new secoiridoids and other anti-hepatitis B virus active constituents from Swertia patens.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,18(6),528-534.
MLA	He, Kang,et al."Two new secoiridoids and other anti-hepatitis B virus active constituents from Swertia patens".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 18.6(2016):528-534.

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