Chemical constituents from Piper hainanense and their cytotoxicities
Shi, Yan-Ni1,2; Xin, Ying1,2; Ling, Yi1,2; Li, Xing-Cong3; Hao, Chao-Yun4; Zhu, Hong-Tao1; Wang, Dong1; Yang, Chong-Ren1; Xu, Min1; Zhang, Ying-Jun1
2016
发表期刊JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
卷号18期号:8页码:730-736
摘要Two new compounds, (Z,R)-1-phenylethylcinnamate (1) and (1R,2R,3R,6S)-pipoxide (2) were isolated from the aerial part of Piper hainanense, along with 12 known compounds, including nine benzene derivatives (4-11), one isobutylamide (12), and two polyoxygenated cyclohexene derivatives (13-14). Their structures were elucidated on the basis of the HRESIMS, 1D and 2D NMR spectroscopic analyses, and ECD in cases of 2 and 3. The absolute configuration of ellipeiopsol B (3) was determined for the first time. All these compounds 1-14 were reported from the titled plant for the first time. Most of the isolates were tested for their cytotoxicities against five human cancer cell lines. Four of which, 2, 3, 9, 14 showed moderate bioactivities. Among them, the new compound 2 showed potential cytotoxicity against SMMC-7721, MCF-7, and SW-480 with IC50 values of 9.7, 15.0, and 13.2M, respectively.
关键词Piperaceae Piper Hainanense Cytotoxicity Polyoxygenated Cyclohexene Derivatives Benzene Derivatives Pipoxide
DOI10.1080/10286020.2016.1158709
收录类别SCI
语种英语
WOS记录号WOS:000379739300003
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/28471
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
3.Univ Mississippi, Sch Pharm, Natl Ctr Nat Prod Res, University, MS 38677 USA
4.Chinese Acad Trop Agr Sci, Inst Spice & Beverage Res, Hainan 100049, Peoples R China
推荐引用方式
GB/T 7714
Shi, Yan-Ni,Xin, Ying,Ling, Yi,et al. Chemical constituents from Piper hainanense and their cytotoxicities[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2016,18(8):730-736.
APA Shi, Yan-Ni.,Xin, Ying.,Ling, Yi.,Li, Xing-Cong.,Hao, Chao-Yun.,...&Zhang, Ying-Jun.(2016).Chemical constituents from Piper hainanense and their cytotoxicities.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,18(8),730-736.
MLA Shi, Yan-Ni,et al."Chemical constituents from Piper hainanense and their cytotoxicities".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 18.8(2016):730-736.
条目包含的文件 下载所有文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
10.1080@10286020.201(893KB)期刊论文作者接受稿开放获取CC BY-NC-SA浏览 下载
10.1080@10286020.201(893KB)期刊论文出版稿开放获取CC BY-NC-SA浏览 下载
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Shi, Yan-Ni]的文章
[Xin, Ying]的文章
[Ling, Yi]的文章
百度学术
百度学术中相似的文章
[Shi, Yan-Ni]的文章
[Xin, Ying]的文章
[Ling, Yi]的文章
必应学术
必应学术中相似的文章
[Shi, Yan-Ni]的文章
[Xin, Ying]的文章
[Ling, Yi]的文章
相关权益政策
暂无数据
收藏/分享
文件名: 10.1080@10286020.2016.1158709.pdf
格式: Adobe PDF
文件名: 10.1080@10286020.2016.1158709.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。