Applanatumols A and B, meroterpenoids with unprecedented skeletons from Ganoderma applanatum
Luo, Qi1,2; Di, Lei1; Yang, Xiao-Hua1,3; Cheng, Yong-Xian1
2016
发表期刊RSC ADVANCES
卷号6期号:51页码:45963-45967
摘要Applanatumols A (1) and B [(+/-)-2], two unique meroterpenoids with a novel spiro[ benzofuran-2,2'-bicyclo [3.2.2]nonane] ring system and a naturally unusual dioxacyclopenta[cd]inden motif, respectively, were isolated from Ganoderma applanatum. Their structures were determined using spectroscopic data. In particular, the absolute configurations of 1 and 2 were assigned by X-ray diffraction analysis using the Flack parameter and ECD calculations, respectively. A plausible biosynthetic pathway for 1 and 2 is proposed. The biological activities of 1 and 2 against renal fibrosis were accessed in rat proximal tubular epithelial cells.
DOI10.1039/c6ra05148k
收录类别SCI
语种英语
WOS记录号WOS:000376120100117
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/26241
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
2.Univ Chinese Acad Sci, Yuquan Rd 19, Beijing 100049, Peoples R China
3.Guangdong Pharmaceut Univ, Guangzhou 510006, Guangdong, Peoples R China
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Luo, Qi,Di, Lei,Yang, Xiao-Hua,et al. Applanatumols A and B, meroterpenoids with unprecedented skeletons from Ganoderma applanatum[J]. RSC ADVANCES,2016,6(51):45963-45967.
APA Luo, Qi,Di, Lei,Yang, Xiao-Hua,&Cheng, Yong-Xian.(2016).Applanatumols A and B, meroterpenoids with unprecedented skeletons from Ganoderma applanatum.RSC ADVANCES,6(51),45963-45967.
MLA Luo, Qi,et al."Applanatumols A and B, meroterpenoids with unprecedented skeletons from Ganoderma applanatum".RSC ADVANCES 6.51(2016):45963-45967.
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