Antioxidant Lignans and Neolignans from Acorus tatarinowii
Lu, Yuanyuan1,2; Xue, Yongbo1; Chen, Shenjie1; Zhu, Hucheng1; Zhang, Jinwen2; Li, Xiao-Nian3; Wang, Jianping1; Liu, JunJun1; Qi, Changxing1; Du, Guang2; Zhang, Yonghui1
2016-03-10
发表期刊SCIENTIFIC REPORTS
卷号6
摘要Eleven new lignans and neolignans, named acortatarinowins G-N (1-8), including three pairs of enantiomers (1a/1b-3a/3b) and five optically pure lignans and neolignans (4-8), along with five known analogs (9-14), were isolated from the rhizomes of Acorus tatarinowii Schott. Compounds 1-3 were successfully separated by chiral HPLC to afford 1a/1b-3a/3b. The planar structures of 1-8 were elucidated by extensive spectroscopic analyses including HRESIMS and NMR. Their absolute configurations were determined by analyses of single-crystal X-ray diffraction and a modified Mosher's method, assisted by experimental and calculated electronic circular dichroism (ECD) data. Compounds 1a and 1b were rare 7,8'-epoxy-8,7'-oxyneolignane. Compounds 1-8 were evaluated for their antioxidant activities using 2,2-diphenyl-1-picrylhydrazyl (DPPH) reducing antioxidant power assay. Compound 6, exhibiting strong DPPH radical scavenging capacity with IC50 value of 16.4 +/- 0.22 mu g/mL, could interpret the herbal traditional usage.
DOI10.1038/srep22909
收录类别SCI
语种英语
WOS记录号WOS:000371669600001
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/26008
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Huazhong Univ Sci & Technol, Sch Pharm, Tongji Med Coll, Hubei Key Lab Nat Med Chem & Resource Evaluat, Wuhan 430030, Hubei Province, Peoples R China
2.Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Wuhan 430030, Hubei Province, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
推荐引用方式
GB/T 7714
Lu, Yuanyuan,Xue, Yongbo,Chen, Shenjie,et al. Antioxidant Lignans and Neolignans from Acorus tatarinowii[J]. SCIENTIFIC REPORTS,2016,6.
APA Lu, Yuanyuan.,Xue, Yongbo.,Chen, Shenjie.,Zhu, Hucheng.,Zhang, Jinwen.,...&Zhang, Yonghui.(2016).Antioxidant Lignans and Neolignans from Acorus tatarinowii.SCIENTIFIC REPORTS,6.
MLA Lu, Yuanyuan,et al."Antioxidant Lignans and Neolignans from Acorus tatarinowii".SCIENTIFIC REPORTS 6(2016).
条目包含的文件 下载所有文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
srep22909.pdf(995KB) 开放获取CC BY-NC-SA浏览 下载
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Lu, Yuanyuan]的文章
[Xue, Yongbo]的文章
[Chen, Shenjie]的文章
百度学术
百度学术中相似的文章
[Lu, Yuanyuan]的文章
[Xue, Yongbo]的文章
[Chen, Shenjie]的文章
必应学术
必应学术中相似的文章
[Lu, Yuanyuan]的文章
[Xue, Yongbo]的文章
[Chen, Shenjie]的文章
相关权益政策
暂无数据
收藏/分享
文件名: srep22909.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。