Evaluation of Anti-MRSA and Xanthine Oxidase Inhibition Activities of Phenolic Constituents from Plumula nelumbinis

doi:10.1155/2015/825792

	Evaluation of Anti-MRSA and Xanthine Oxidase Inhibition Activities of Phenolic Constituents from Plumula nelumbinis
	Ding, Xiao; Ouyang, Ming-An; Shen, Yuan-Shuai
	2015
发表期刊	JOURNAL OF CHEMISTRY
摘要	Isolation of metabolites from Plumula nelumbinis led to the discovery of eleven compounds, including six flavonoids and five phenolderivatives. Their structures have been determined on the basis of chemical and spectroscopic data. Most of them, such as compounds 1, 4, 6, 8, and 10, have shown inhibitory activity against hospital-acquired methicillin-resistant Staphylococcus aureus (HA-MRSA). MICs of compound 8 against SA-200195 and SA-300150 were 2 mu g/mL and 8 mu g/mL, respectively. And the antioxidant activity of isolated compounds was determined by checking the scavenging activity against three different radicals: 2,2-diphenyl-1-picrydrazyl (DPPH) radical, hydroxyl radical ((OH)-O-center dot), and superoxide anion (O-2(center dot-)), as well as xanthine oxidase inhibition. All flavonoids showed strong antioxidant activity. And compound 6 displayed the highest inhibitory effect against xanthine oxidase with IC50 value of 8.2 mu g/mL.
DOI	10.1155/2015/825792
收录类别	SCI
语种	英语
WOS记录号	WOS:000367627800001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/25444
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Ding, Xiao,Ouyang, Ming-An,Shen, Yuan-Shuai. Evaluation of Anti-MRSA and Xanthine Oxidase Inhibition Activities of Phenolic Constituents from Plumula nelumbinis[J]. JOURNAL OF CHEMISTRY,2015.
APA	Ding, Xiao,Ouyang, Ming-An,&Shen, Yuan-Shuai.(2015).Evaluation of Anti-MRSA and Xanthine Oxidase Inhibition Activities of Phenolic Constituents from Plumula nelumbinis.JOURNAL OF CHEMISTRY.
MLA	Ding, Xiao,et al."Evaluation of Anti-MRSA and Xanthine Oxidase Inhibition Activities of Phenolic Constituents from Plumula nelumbinis".JOURNAL OF CHEMISTRY (2015).

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