Limonoids from Munronia henryi and their anti-tobacco mosaic virus activity
Yan, Ying; Yuan, Chun-Mao; Di, Ying-Tong; Huang, Tao; Fan, Yi-Min; Ma, Yuan; Zhang, Jian-Xin; Hao, Xiao-Jiang
2015-12-01
发表期刊FITOTERAPIA
卷号107页码:29-35
摘要Five new compounds (1-5), including three limonoids, one diterpenoid, and one phytosterol, along with four known limonoids (6-9), were isolated from the ethanolic extracts of whole plants of Munronia henryi. Their structures were elucidated by extensive spectroscopic analysis. In addition, the anti-tobacco mosaic virus (TMV) activities of all the isolated compounds were evaluated by the conventional half-leaf and leaf-disk methods along with Western blot analysis. Most of the tested compounds showed strong antiviral activities, with IC50 values in the range of 14.8-34.0 mu g/mL, compared with ningnanmycin as a positive control (IC50 = 44.6 mu g/mL), and their preliminary structure-activity relationships were also discussed. (C) 2015 Elsevier B.V. All rights reserved.
关键词Munronia Henryi Limonoids Anti-tobacco Mosaic Virus (Tmv) Activity Western Blot Structure-activity Relationship
DOI10.1016/j.fitote.2015.09.016
收录类别SCI
语种英语
WOS记录号WOS:000367113000004
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/25335
专题植物化学与西部植物资源持续利用国家重点实验室
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Yan, Ying,Yuan, Chun-Mao,Di, Ying-Tong,et al. Limonoids from Munronia henryi and their anti-tobacco mosaic virus activity[J]. FITOTERAPIA,2015,107:29-35.
APA Yan, Ying.,Yuan, Chun-Mao.,Di, Ying-Tong.,Huang, Tao.,Fan, Yi-Min.,...&Hao, Xiao-Jiang.(2015).Limonoids from Munronia henryi and their anti-tobacco mosaic virus activity.FITOTERAPIA,107,29-35.
MLA Yan, Ying,et al."Limonoids from Munronia henryi and their anti-tobacco mosaic virus activity".FITOTERAPIA 107(2015):29-35.
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