Anti-HIV terpenoids from Daphne aurantiaca Diels. stems
Huang, Sheng-Zhuo1; Zhang, Xuan2; Ma, Qing-Yun1; Zheng, Yong-Tang2; Dai, Hao-Fu1; Wang, Qi1; Zhou, Jun3; Zhao, You-Xing1
2015
Source PublicationRSC ADVANCES
Volume5Issue:98Pages:80254-80263
AbstractThirteen new sesquiterpenoids, including six guaiane type auranticanols A-F (1, 2, and 4-7) and seven carotene type auranticanols G-M (18-24) were isolated from the stems of Daphne aurantiaca Diels., along with fourteen known sesquiterpenoids (3, 8-17, 25-27) and two known tigliane diterpenoids (28, 29), and their structures were elucidated by extensively analyzing their MS and NMR spectroscopic data. A bioassay of anti-HIV activity indicated that compounds 11, 14, 19, and 28 showed definite activities with EC50 values of 2.138, 0.286, 1.773 and 0.000282 mu g mL(-1) and SI > 93.545, 93.787, 10.243, and 65 177.305, respectively.
DOI10.1039/c5ra17099k
Indexed BySCI
Language英语
WOS IDWOS:000362409800021
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/25188
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Minist Agr, Key Lab Biol & Genet Resources Trop Crops, Haikou 571101, Peoples R China
2.Chinese Acad Sci, Kunming Inst Zool, KIZ CUHK Joint Lab Bioresources & Mol Res Common, Key Lab Anim Models & Human Dis Mech Chinese Acad, Kunming 650204, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
Recommended Citation
GB/T 7714
Huang, Sheng-Zhuo,Zhang, Xuan,Ma, Qing-Yun,et al. Anti-HIV terpenoids from Daphne aurantiaca Diels. stems[J]. RSC ADVANCES,2015,5(98):80254-80263.
APA Huang, Sheng-Zhuo.,Zhang, Xuan.,Ma, Qing-Yun.,Zheng, Yong-Tang.,Dai, Hao-Fu.,...&Zhao, You-Xing.(2015).Anti-HIV terpenoids from Daphne aurantiaca Diels. stems.RSC ADVANCES,5(98),80254-80263.
MLA Huang, Sheng-Zhuo,et al."Anti-HIV terpenoids from Daphne aurantiaca Diels. stems".RSC ADVANCES 5.98(2015):80254-80263.
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