Nodulisporisteroids C-L, new 4-methyl-progesteroid derivatives from Nodulisporium sp.

doi:10.1016/j.steroids.2015.08.004

	Nodulisporisteroids C-L, new 4-methyl-progesteroid derivatives from Nodulisporium sp.
	Zhao,Qin; Wang,Gao-Qian; Chen,Guo-Dong; Hu,Dan; Li,Xiao-Xia; Guo,Liang-Dong; Li,Yan; Yao,Xin-Sheng; Gao,Hao
	2015-10-01
发表期刊	STEROIDS
卷号	102 页码:101-109
摘要	The fungus Nodulisporium sp. (No. 65-12-7-1), which can produce a rare class of steroids (4-methyl-progesteroids) in rice solid medium, was subjected to a one strain-many compounds (OSMAC) approach. It was found to produce ten new 4-methyl-progesteroid derivatives named nodulisporisteroids C-L (1-10) in potato-dextrose-broth (PDB) medium, which showed that the fungus was a prolific producer of 4-methyl-progesteroids. The structures of 1-10 were elucidated by spectroscopic and X-ray crystallographic analysis. Their cytotoxic activities against five human cancer cell lines had been evaluated using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method. (C) 2015 Elsevier Inc. All rights reserved.
关键词	Xylariaceae NoduliSp.rium Sp. Endolichenic Fungus 4-methyl-progesteroid Derivatives
DOI	10.1016/j.steroids.2015.08.004
收录类别	SCI
语种	英语
WOS记录号	WOS:000361251300014
引用统计	被引频次：22[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/25144
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Zhao,Qin,Wang,Gao-Qian,Chen,Guo-Dong,et al. Nodulisporisteroids C-L, new 4-methyl-progesteroid derivatives from Nodulisporium sp.[J]. STEROIDS,2015,102:101-109.
APA	Zhao,Qin.,Wang,Gao-Qian.,Chen,Guo-Dong.,Hu,Dan.,Li,Xiao-Xia.,...&Gao,Hao.(2015).Nodulisporisteroids C-L, new 4-methyl-progesteroid derivatives from Nodulisporium sp..STEROIDS,102,101-109.
MLA	Zhao,Qin,et al."Nodulisporisteroids C-L, new 4-methyl-progesteroid derivatives from Nodulisporium sp.".STEROIDS 102(2015):101-109.

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