Nonpeptide small molecules from the insect Aspongopus chinensis and their neural stem cell proliferation stimulating properties

doi:10.1039/c5ra12920f

	Nonpeptide small molecules from the insect Aspongopus chinensis and their neural stem cell proliferation stimulating properties
	Di, Lei 1; Shi, Yan-Ni 1,2; Yan, Yong-Ming 1,2; Jiang, Li-Ping 2,3; Hou, Bo 1; Wang, Xin-Long 1; Zuo, Zhi-Li1 ; Chen, Yong-Bin 3; Yang, Cui-Ping 3; Cheng, Yong-Xian 1
	2015
发表期刊	RSC ADVANCES
卷号	5 期号:87 页码:70985-70991
摘要	Four pairs of enantiomeric hypoxanthine analogues (1, 2, 5 and 6), two pairs of enantiomeric adenine analogues (3 and 4), two pyrazines, aspongpyrazines A (7) and B (8), and a pair of glycerides ((+)-9 and (-)-9), along with twenty-eight known substances were isolated from the insect Aspongopus chinensis. The structures of the new natural products were assigned by using spectroscopic and computational methods. Chiral HPLC was used to separate the (-)- and (+)-antipodes of 1-6, and 9. Several of the new, A. chinensis derived natural products were found to promote proliferation of neural stem cells (NSCs) at a concentration of 10 mu M.
DOI	10.1039/c5ra12920f
收录类别	SCI
语种	英语
WOS记录号	WOS:000360445500034
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/25121
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci & Yunnan Prov, Kunming Inst Zool, Key Lab Anim Models & Human Dis Mech, Kunming 650223, Peoples R China
推荐引用方式 GB/T 7714	Di, Lei,Shi, Yan-Ni,Yan, Yong-Ming,et al. Nonpeptide small molecules from the insect Aspongopus chinensis and their neural stem cell proliferation stimulating properties[J]. RSC ADVANCES,2015,5(87):70985-70991.
APA	Di, Lei.,Shi, Yan-Ni.,Yan, Yong-Ming.,Jiang, Li-Ping.,Hou, Bo.,...&Cheng, Yong-Xian.(2015).Nonpeptide small molecules from the insect Aspongopus chinensis and their neural stem cell proliferation stimulating properties.RSC ADVANCES,5(87),70985-70991.
MLA	Di, Lei,et al."Nonpeptide small molecules from the insect Aspongopus chinensis and their neural stem cell proliferation stimulating properties".RSC ADVANCES 5.87(2015):70985-70991.

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