Nonpeptide small molecules from the insect Aspongopus chinensis and their neural stem cell proliferation stimulating properties
Di, Lei1; Shi, Yan-Ni1,2; Yan, Yong-Ming1,2; Jiang, Li-Ping2,3; Hou, Bo1; Wang, Xin-Long1; Zuo, Zhi-Li1; Chen, Yong-Bin3; Yang, Cui-Ping3; Cheng, Yong-Xian1
2015
发表期刊RSC ADVANCES
卷号5期号:87页码:70985-70991
摘要Four pairs of enantiomeric hypoxanthine analogues (1, 2, 5 and 6), two pairs of enantiomeric adenine analogues (3 and 4), two pyrazines, aspongpyrazines A (7) and B (8), and a pair of glycerides ((+)-9 and (-)-9), along with twenty-eight known substances were isolated from the insect Aspongopus chinensis. The structures of the new natural products were assigned by using spectroscopic and computational methods. Chiral HPLC was used to separate the (-)- and (+)-antipodes of 1-6, and 9. Several of the new, A. chinensis derived natural products were found to promote proliferation of neural stem cells (NSCs) at a concentration of 10 mu M.
DOI10.1039/c5ra12920f
收录类别SCI
语种英语
WOS记录号WOS:000360445500034
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被引频次:21[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/25121
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Chinese Acad Sci & Yunnan Prov, Kunming Inst Zool, Key Lab Anim Models & Human Dis Mech, Kunming 650223, Peoples R China
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Di, Lei,Shi, Yan-Ni,Yan, Yong-Ming,et al. Nonpeptide small molecules from the insect Aspongopus chinensis and their neural stem cell proliferation stimulating properties[J]. RSC ADVANCES,2015,5(87):70985-70991.
APA Di, Lei.,Shi, Yan-Ni.,Yan, Yong-Ming.,Jiang, Li-Ping.,Hou, Bo.,...&Cheng, Yong-Xian.(2015).Nonpeptide small molecules from the insect Aspongopus chinensis and their neural stem cell proliferation stimulating properties.RSC ADVANCES,5(87),70985-70991.
MLA Di, Lei,et al."Nonpeptide small molecules from the insect Aspongopus chinensis and their neural stem cell proliferation stimulating properties".RSC ADVANCES 5.87(2015):70985-70991.
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