Three new phenanthrenone constituents from Trigonostemon lii

doi:10.1080/14786419.2015.1009066

	Three new phenanthrenone constituents from Trigonostemon lii
	Li,Shi-Fei; He,Hong-Ping; Hao,Xiao-Jiang
	2015-10-02
发表期刊	NATURAL PRODUCT RESEARCH
卷号	29 期号:19 页码:1845-1849
摘要	Three new phenanthrenone constituents, trigoxyphins U-W (1, 7 and 9), together with eight known ones, trigoxyphin M (2), 6,9-O-dimethyltrigonostemone (3), trigonstemone (4), thrigonosomone B (5), trigonochinene E (6), actephiiol A (8), epiactephilol A (10) and neoboutomannin (11), were obtained from the methanol extract of the leaves and stems of Trigonostemonlii. The structures of the new metabolites were elucidated by analysing the spectroscopic data (1D NMR, 2D NMR, HR-ESI-MS and IR). Compounds 1-6 were evaluated for their cytotoxic activities on five human tumour cell lines by using the MTT method, and compound 1 exhibited inhibitory activity against HL-60, SMMC-7721, A-549, MCF-7 and SW480 with IC50 values ranging from 3.77 to 14.51M.
关键词	Euphorbiaceae Trigonostemonlii Phenanthrenone Trigoxyphins U-w Cytotoxic Activity
DOI	10.1080/14786419.2015.1009066
收录类别	SCI
语种	英语
WOS记录号	WOS:000360458600011
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/25119
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Li,Shi-Fei,He,Hong-Ping,Hao,Xiao-Jiang. Three new phenanthrenone constituents from Trigonostemon lii[J]. NATURAL PRODUCT RESEARCH,2015,29(19):1845-1849.
APA	Li,Shi-Fei,He,Hong-Ping,&Hao,Xiao-Jiang.(2015).Three new phenanthrenone constituents from Trigonostemon lii.NATURAL PRODUCT RESEARCH,29(19),1845-1849.
MLA	Li,Shi-Fei,et al."Three new phenanthrenone constituents from Trigonostemon lii".NATURAL PRODUCT RESEARCH 29.19(2015):1845-1849.

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