Sesquiterpenoids from Pilea cavaleriei subsp crenata
Tang, Gui-Hua1,2; Sun, Chang-Song3; Long, Chun-Lin1,4; Li, Ma-Lin3; Wang, Yue-Hu1; Luo, Min3; Wang, Hong-Sheng1,5,6; Shi, Ya-Na1,5
2009-10-01
发表期刊BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN0960-894X
卷号19期号:19页码:5737-5740
摘要Three new humulane-type sesquiterpenes, 8-O-(p-coumaroyl)-5 beta-hydroperoxy-1(10)E,4(15)-humuladien-8 alpha-ol (1), 8-O-(3-nitro-p-coumaroyl)-1(10)E, 4(15)-humuladien-5 beta,8 alpha-diol (2) and 8-O-(p-coumaroyl)-1(10)E,4(5)E-humuladien-8-ol (3), and a new copaborneol derivative, 1-O-p-coumaroyl-copaborneol (4), have been isolated from the methanol extract of Pilea cavaleriei Levl. subsp. crenata C.J. Chen. Their structures were elucidated using spectroscopic methods. Cytotoxic and antimicrobial activities of the isolated compounds were evaluated. (C) 2009 Elsevier Ltd. All rights reserved.
关键词Pilea Sesquiterpenoids Humulane Copaborneol
资助信息This work was funded by grants of the Ministry of Education of China through its 111 & 985 projects (B08044 & CUN 985-3-3), the Ministry of Science and Technology of China (2008FY110400-2-2 & 2005DKA21006), and the Knowledge Innovation Program of the Chinese Academy of Sciences. We thank Dr. Qian-Yun Sun and the staff of the Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences for carrying out the cytotoxicity evaluation (A549 and MCF-7 cells) and antimicrobial assays.
学科领域Chemistry, Medicinal ; Chemistry, Organic
DOI10.1016/j.bmcl.2009.08.001
收录类别SCI
语种英语
WOS研究方向Pharmacology & Pharmacy ; Chemistry
WOS类目Chemistry, Medicinal ; Chemistry, Organic
WOS记录号WOS:000270106700048
引用统计
被引频次:7[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/2417
专题资源植物与生物技术所级重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China
3.Kunming Med Coll, Kunming 650031, Yunnan, Peoples R China
4.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China
5.Yunnan Agr Univ, Kunming 650201, Peoples R China
6.Henan Inst Sci & Technol, Xinxiang 453003, Peoples R China
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Tang, Gui-Hua,Sun, Chang-Song,Long, Chun-Lin,et al. Sesquiterpenoids from Pilea cavaleriei subsp crenata[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2009,19(19):5737-5740.
APA Tang, Gui-Hua.,Sun, Chang-Song.,Long, Chun-Lin.,Li, Ma-Lin.,Wang, Yue-Hu.,...&Shi, Ya-Na.(2009).Sesquiterpenoids from Pilea cavaleriei subsp crenata.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,19(19),5737-5740.
MLA Tang, Gui-Hua,et al."Sesquiterpenoids from Pilea cavaleriei subsp crenata".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 19.19(2009):5737-5740.
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