Megathyrin B: A cytotoxic diterpene from Isodon megathyrsus

	Megathyrin B: A cytotoxic diterpene from Isodon megathyrsus
	Qiu, SX ; Sun, HD; Lobkovsky, E ; Chai, H ; Clardy, I ; Farnsworth, NR ; Pezzuto, JM ; Fong, HHS
	1998-12-01
发表期刊	PLANTA MEDICA
卷号	64 期号:8 页码:728-731
摘要	From the leaves of Isodon megothyrsus, a novel entkaurene diterpene, megathyrin B, was isolated and its structure determined as 1 alpha,7 beta,11 beta,15 beta-tetrahydroxy-ent-7 alpha,20-epoxykaur-16-ene by 1D- and 2D-NMR spectral analysis. Additionally, its stereochemistry was unambiguously assigned by X-ray crystallography. This compound was cytotoxic to the KB and KB-V cell lines.
关键词	Isodon Megathyrsus Labiatae Leaves Ent-kaurene Diterpene Human Cancer Lines Cytotoxic Activity 2d-nmr Techniques X-ray Crystallography Megathyrin b Electrospray Lc/ms
收录类别	SCI
语种	英语
WOS记录号	WOS:000077915200010
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/23958
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Univ Illinois, Coll Pharm, Program Collaborat Res Pharmaceut Sci, Chicago, IL 60612 USA 2.Chinese Acad Sci, Kunming Inst Bot, Kunming, Peoples R China 3.Cornell Univ, Baker Lab, Dept Chem, Ithaca, NY 14853 USA
推荐引用方式 GB/T 7714	Qiu, SX,Sun, HD,Lobkovsky, E,et al. Megathyrin B: A cytotoxic diterpene from Isodon megathyrsus[J]. PLANTA MEDICA,1998,64(8):728-731.
APA	Qiu, SX.,Sun, HD.,Lobkovsky, E.,Chai, H.,Clardy, I.,...&Fong, HHS.(1998).Megathyrin B: A cytotoxic diterpene from Isodon megathyrsus.PLANTA MEDICA,64(8),728-731.
MLA	Qiu, SX,et al."Megathyrin B: A cytotoxic diterpene from Isodon megathyrsus".PLANTA MEDICA 64.8(1998):728-731.

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