Cytotoxic Indole Alkaloids from Melodinus tenuicaudatus
Feng, Tao1,2; Li, Yan1; Wang, Yuan-Yuan1; Cai, Xiang-Hai1; Liu, Ya-Ping1,2; Luo, Xiao-Dong1
2010-06-01
发表期刊JOURNAL OF NATURAL PRODUCTS
卷号73期号:6页码:1075-1079
摘要Four new bisindole alkaloids, melodinines H-K (1-4), a new monomer, melodinine L (5), and 11 known alkaloids were isolated from Melodinus tenuicaudatus. The structures of 1-5 were elucidated by extensive spectroscopic methods, and the known compounds were identified by comparison with data in the literature. All of the compounds were evaluated for their cytotoxicity against five human cancer cell lines, Alkaloids 3, and 4 and the known compound 11-methoxytabersonine (8) exhibited inhibitory effects, with IC(50) values comparable to those of cisplatin and vinorelbine.
DOI10.1021/np100086x
收录类别SCI
语种英语
WOS记录号WOS:000279070300010
引用统计
被引频次:66[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/23916
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
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Feng, Tao,Li, Yan,Wang, Yuan-Yuan,et al. Cytotoxic Indole Alkaloids from Melodinus tenuicaudatus[J]. JOURNAL OF NATURAL PRODUCTS,2010,73(6):1075-1079.
APA Feng, Tao,Li, Yan,Wang, Yuan-Yuan,Cai, Xiang-Hai,Liu, Ya-Ping,&Luo, Xiao-Dong.(2010).Cytotoxic Indole Alkaloids from Melodinus tenuicaudatus.JOURNAL OF NATURAL PRODUCTS,73(6),1075-1079.
MLA Feng, Tao,et al."Cytotoxic Indole Alkaloids from Melodinus tenuicaudatus".JOURNAL OF NATURAL PRODUCTS 73.6(2010):1075-1079.
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