Cytotoxic Indole Alkaloids from Melodinus tenuicaudatus | |
Feng, Tao1,2; Li, Yan1; Wang, Yuan-Yuan1; Cai, Xiang-Hai1; Liu, Ya-Ping1,2; Luo, Xiao-Dong1 | |
2010-06-01 | |
发表期刊 | JOURNAL OF NATURAL PRODUCTS |
卷号 | 73期号:6页码:1075-1079 |
摘要 | Four new bisindole alkaloids, melodinines H-K (1-4), a new monomer, melodinine L (5), and 11 known alkaloids were isolated from Melodinus tenuicaudatus. The structures of 1-5 were elucidated by extensive spectroscopic methods, and the known compounds were identified by comparison with data in the literature. All of the compounds were evaluated for their cytotoxicity against five human cancer cell lines, Alkaloids 3, and 4 and the known compound 11-methoxytabersonine (8) exhibited inhibitory effects, with IC(50) values comparable to those of cisplatin and vinorelbine. |
DOI | 10.1021/np100086x |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000279070300010 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/23916 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China |
推荐引用方式 GB/T 7714 | Feng, Tao,Li, Yan,Wang, Yuan-Yuan,et al. Cytotoxic Indole Alkaloids from Melodinus tenuicaudatus[J]. JOURNAL OF NATURAL PRODUCTS,2010,73(6):1075-1079. |
APA | Feng, Tao,Li, Yan,Wang, Yuan-Yuan,Cai, Xiang-Hai,Liu, Ya-Ping,&Luo, Xiao-Dong.(2010).Cytotoxic Indole Alkaloids from Melodinus tenuicaudatus.JOURNAL OF NATURAL PRODUCTS,73(6),1075-1079. |
MLA | Feng, Tao,et al."Cytotoxic Indole Alkaloids from Melodinus tenuicaudatus".JOURNAL OF NATURAL PRODUCTS 73.6(2010):1075-1079. |
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