| Phytochemical analysis of an antiviral fraction of Radix astragali using HPLC-DAD-ESI-MS/MS | |
| Tang, Li1; Liu, Ying1; Wang, Yeling1; Long, Chunlin1,2 | |
| 通讯作者 | tangli1973@yahoo.com.cn |
| 2010-04-01 | |
| 发表期刊 | JOURNAL OF NATURAL MEDICINES
 |
| ISSN | 1340-3443 |
| 卷号 | 64期号:2页码:182-186 |
| 摘要 | Radix astragali (Huangqi in Chinese) is a well-known traditional Chinese medicinal herb that has been used clinically in China for centuries to cure various diseases. To profile the antiviral constituents of this herb, a high-performance liquid chromatography-diode array detector-electrospray ionization-tandem mass spectrometry (HPLC-DAD-ESI-MS/MS) analytical method was developed to separate and determinate the active part of the extract of Radix astragali, which showed potent inhibition of several viruses. By comparing their retention time and MS data with those obtained from the authentic compounds and the published data, a total of 18 compounds, comprising 11 flavonoids and 7 saponins, were identified. This study provides an approach to rapidly characterize bioactive constituents in traditional Chinese medicines (TCMs). |
| 关键词 | Radix Astragali Antiviral Activity Flavonoid Saponin Hplc-dad-esi-ms/ms |
| 学科领域 | Chemistry, Medicinal ; Pharmacology & Pharmacy |
| DOI | 10.1007/s11418-009-0381-1 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000275691600010 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/2315 |
| 专题 | 资源植物与生物技术所级重点实验室 |
| 作者单位 | 1.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tang, Li,Liu, Ying,Wang, Yeling,et al. Phytochemical analysis of an antiviral fraction of Radix astragali using HPLC-DAD-ESI-MS/MS[J]. JOURNAL OF NATURAL MEDICINES,2010,64(2):182-186. |
| APA | Tang, Li,Liu, Ying,Wang, Yeling,&Long, Chunlin.(2010).Phytochemical analysis of an antiviral fraction of Radix astragali using HPLC-DAD-ESI-MS/MS.JOURNAL OF NATURAL MEDICINES,64(2),182-186. |
| MLA | Tang, Li,et al."Phytochemical analysis of an antiviral fraction of Radix astragali using HPLC-DAD-ESI-MS/MS".JOURNAL OF NATURAL MEDICINES 64.2(2010):182-186. |
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