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题名: Phytochemical analysis of an antiviral fraction of Radix astragali using HPLC-DAD-ESI-MS/MS
作者: Tang, Li1; Liu, Ying1; Wang, Yeling1; Long, Chunlin1, 2
刊名: JOURNAL OF NATURAL MEDICINES
关键词: Radix astragali ; Antiviral activity ; Flavonoid ; Saponin ; HPLC-DAD-ESI-MS/MS
英文摘要: Radix astragali (Huangqi in Chinese) is a well-known traditional Chinese medicinal herb that has been used clinically in China for centuries to cure various diseases. To profile the antiviral constituents of this herb, a high-performance liquid chromatography-diode array detector-electrospray ionization-tandem mass spectrometry (HPLC-DAD-ESI-MS/MS) analytical method was developed to separate and determinate the active part of the extract of Radix astragali, which showed potent inhibition of several viruses. By comparing their retention time and MS data with those obtained from the authentic compounds and the published data, a total of 18 compounds, comprising 11 flavonoids and 7 saponins, were identified. This study provides an approach to rapidly characterize bioactive constituents in traditional Chinese medicines (TCMs).
出版日期: 2010-04-01
卷号: 64, 期号:2, 页码:182-186
语种: 英语
收录类别: SCI
学科分类: Chemistry, Medicinal; Pharmacology & Pharmacy
ISSN号: 1340-3443
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/2315
Appears in Collections:资源植物与生物技术所级重点实验室_期刊论文

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作者单位: 1.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China

Recommended Citation:
Tang, L; Liu, Y; Wang, YL; Long, CL.Phytochemical analysis of an antiviral fraction of Radix astragali using HPLC-DAD-ESI-MS/MS,JOURNAL OF NATURAL MEDICINES,2010,64(2):182-186
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