Pyrrolidinoindoline Alkaloids from Selaginella moellendorfii
Wang, Yue-Hu1; Long, Chun-Lin1,2; Yang, Fu-Mei5; Wang, Xi5; Sun, Qian-Yun5; Wang, Hong-Sheng1,3,4; Shi, Ya-Na1,3; Tang, Gui-Hua1
2009-06-01
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号72期号:6页码:1151-1154
摘要Eight new pyrrolidinoindoline alkaloids (1-8) were isolated from the whole plant of Selaginella moellendorfii. Their structures were determined by mass spectrometry, 1D and 2D NMR spectroscopy, and chemical interconversions. These alkaloids have a 3-carboxybut-2-enyl group at C-3a and two methyl groups at N-8. The possible biogenetic route front selaginellic acid (1) to neoselaginellic acid (6) was postulated and chemically mimicked. Tautomerization between 6 and 6a was observed. Selected compounds were evaluated for antibacterial, cytotoxic, and acetylcholinesterase inhibitory activities.
资助信息This work was financially supported by the Ministry of Education of China through its 111 & 985 projects (1308044 & MUC 985-3-3), the Ministry of Science and Technology of China (2005DKA21006), and the Knowledge Innovation Program of the Chinese Academy of Sciences. Selena Ahmed, a Ph.D. candidate in Biology at the City University of New York, helped edit the English of this paper.
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1021/np9001515
收录类别SCI ; IC
语种英语
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000267432600031
引用统计
被引频次:36[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/2313
专题资源植物与生物技术所级重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China
2.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China
3.Yunnan Agr Univ, Kunming 650201, Peoples R China
4.Henan Inst Sci & Tcchnol, Xinxiang 453003, Peoples R China
5.Chinese Acad Sci, Guiyang 550002, Peoples R China
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Wang, Yue-Hu,Long, Chun-Lin,Yang, Fu-Mei,et al. Pyrrolidinoindoline Alkaloids from Selaginella moellendorfii[J]. JOURNAL OF NATURAL PRODUCTS,2009,72(6):1151-1154.
APA Wang, Yue-Hu.,Long, Chun-Lin.,Yang, Fu-Mei.,Wang, Xi.,Sun, Qian-Yun.,...&Tang, Gui-Hua.(2009).Pyrrolidinoindoline Alkaloids from Selaginella moellendorfii.JOURNAL OF NATURAL PRODUCTS,72(6),1151-1154.
MLA Wang, Yue-Hu,et al."Pyrrolidinoindoline Alkaloids from Selaginella moellendorfii".JOURNAL OF NATURAL PRODUCTS 72.6(2009):1151-1154.
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