|Antibacterial constituents from Melodinus suaveolens|
|Li, J. L.; Lunga, P. K.; Zhao, Y. L.; Qin, X. J.; Luo, X. D.; Liu,YP (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.; firstname.lastname@example.org; email@example.com
|发表期刊||CHINESE JOURNAL OF NATURAL MEDICINES
|摘要||To investigate the non-alkaloidal chemical constituents of the stems and leaves of Melodinus suaveolens and their antibacterial activities. Compounds were isolated and purified by repeated silica gel, Sephadex LH-20, RP18, and preparative HPLC. Their structures were elucidated by comparison with published spectroscopic data, as well as on the basis of extensive spectroscopic analysis. The antibacterial screening assays were performed by the dilution method. Fourteen compounds were isolated, and identified as lycopersene (1). betulinic aldehyde (2), 3 beta-acctoxy-22,23,24,25,26,27-hexanordammaran-20-one(3), 3a-acetyl-2, 3, 5-trimethyl-7a-hydroxy-5-(4,8, 12-trimethyl-tridecanyl)-1,3a, 5,6,7,7a-hexahydro- 4-oxainden-1-one (4), 3 beta-hydroxy-28-norlup-20(29)-ene-17 beta-hydroperoxide (5), 3 beta-hydroxy-28-norlup-20(29)-ene-17 alpha-hydroperoxide (6), beta-sitosterol (7), 28-nor-urs-12-ene-3 beta, 17 beta-diol (8), alpha-amyrin (9), ergosta-4,6,8(14) 22-tetraen-3-one (10), 3 beta-hydroxy-urs-11-en-28,13 beta-olide (11), betulin (12), obtusalin (13), and ursolic acid (14), Among the isolates,. compounds 1, 2. 6, 8, 10, and 14 showed potent antibacterial activities against the four bacteria, This is the first report of the antibacterial activity of the constituents of Melodinus suaveolens|
Non-alkaloidal Chemical Constituents
|资助信息||Natural Science Foundation of China ; National Science and Technology Support Program of China [2013BAI11B02]|
|通讯作者||Liu,YP (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.; firstname.lastname@example.org; email@example.com|
|作者单位||Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China|
Li, J. L.,Lunga, P. K.,Zhao, Y. L.,et al. Antibacterial constituents from Melodinus suaveolens[J]. CHINESE JOURNAL OF NATURAL MEDICINES,2015,13(4):307-310.
Li, J. L..,Lunga, P. K..,Zhao, Y. L..,Qin, X. J..,Luo, X. D..,...&firstname.lastname@example.org.(2015).Antibacterial constituents from Melodinus suaveolens.CHINESE JOURNAL OF NATURAL MEDICINES,13(4),307-310.
Li, J. L.,et al."Antibacterial constituents from Melodinus suaveolens".CHINESE JOURNAL OF NATURAL MEDICINES 13.4(2015):307-310.