Du,ZZ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.
Three new dinormonoterpenoid glucosides, rel-(3R, 4R)-3-(1-hydroxypropan-2-yl)-3,4-epoxypentane1,5-diol-1-O-beta-D-glucopyranoside (1), rel-(3R, 4S)-3-(1-hydroxypropan-2-yl)-3,4-epoxypentane-1,5-diol-1-O-beta-D-glucopyranoside (2), and rel-(3R, 4S)-3-(1-hydroxy-2-propen-2-yl)-3,4-epoxypentane-1,5-diol-1-O-beta-D-glucopyranoside (3), were isolated from the edible pericarps of Myriopteron extensum (Wight & Arn.) K. Schum. (Asclepiadaceae). Their structures were elucidated by chemical and spectroscopic methods including HRESIMS, 1D and 2D NMR. Dinormonoterpenoid glucosides were reported from Asclepiadaceae for the first time. Compounds 1-3 were evaluated for their cytotoxicity against five human cancer cell lines HL-60, SMMC-7221, A-549, MCF-7, and SW-480, but they did not exhibit cytotoxicity on the tested cell lines. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
Natural Science Foundation of the Yunnan Province [2013FB065]
; 45th Scientific Research Foundation for the Returned Overseas Chinese Scholars from State Education Ministry
; National Science and Technology Support Program of China [2013BAI11B02]