Mixed lignan-neolignans from Tarenna attenuata

doi:10.1021/np0603931

	Mixed lignan-neolignans from Tarenna attenuata
	Yang, Xian-Wen ; Zhao, Pei-Ji ; Ma, Yan-Lin ; Xiao, Hai-Tao ; Zuo, Yi-Qing ; He, Hong-Ping ; Li, Ling ; Hao, Xiao-Jiang
	2007-04-01
发表期刊	JOURNAL OF NATURAL PRODUCTS
ISSN	0163-3864
卷号	70 期号:4 页码:521-525
摘要	Six new mixed lignan-neolignans and 20 known compounds were isolated from the whole plant of Tarenna attenuata. By analysis of physical and spectroscopic data, the structures of the new compounds were elucidated as (1R,5R,6R)-6-{4-O-[2-(1-(4-hydroxy-3-methoxyphenyl))glycerol]-3,5-dimethoxyphenyl}-3,7-dioxabicyclo[3.3.0]octan-2-one (1), 5' '-methoxyhedyotisol A (2), 4' '-O-(8-guaiacylglycerol)buddlenol A (3), 5' '-methoxy-4' '-O-(8-guaiacylglycerol)buddlenol A (4), 4,6-dimethoxy-5-hydroxy-3-hydroxymethyl-2-(3,4,5-trimethoxyphenyl)-2,3-dihydrobenzofuran (5), and 7-O-ethylguaiacylglycerol (6). Compounds 1, 5, 6, and 8 showed potent antioxidant activities against H2O2-induced impairment in PC12 cells, and compounds 1, 2, 5, and 7 scavenged DPPH radical strongly with IC50 values of 72, 87, 45, and 55 mu M, respectively.
关键词	Medicinal-plants Constituents
学科领域	Plant Sciences ; Chemistry ; Medicinal ; Pharmacology & Pharmacy
DOI	10.1021/np0603931
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000246007200005
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/2085
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Second Mil Med Univ, Dept Nat Prod Chem, Sch Pharm, Shanghai 200433, Peoples R China 3.Kunming Med Coll, Yunnan Pharmacol Labs Nat Prod, Kunming 650031, Peoples R China 4.Guiyang Med Coll, Sch Pharm, Guiyang 550004, Peoples R China
推荐引用方式 GB/T 7714	Yang, Xian-Wen,Zhao, Pei-Ji,Ma, Yan-Lin,et al. Mixed lignan-neolignans from Tarenna attenuata[J]. JOURNAL OF NATURAL PRODUCTS,2007,70(4):521-525.
APA	Yang, Xian-Wen.,Zhao, Pei-Ji.,Ma, Yan-Lin.,Xiao, Hai-Tao.,Zuo, Yi-Qing.,...&Hao, Xiao-Jiang.(2007).Mixed lignan-neolignans from Tarenna attenuata.JOURNAL OF NATURAL PRODUCTS,70(4),521-525.
MLA	Yang, Xian-Wen,et al."Mixed lignan-neolignans from Tarenna attenuata".JOURNAL OF NATURAL PRODUCTS 70.4(2007):521-525.

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