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题名: Mixed lignan-neolignans from Tarenna attenuata
作者: Yang, Xian-Wen; Zhao, Pei-Ji; Ma, Yan-Lin; Xiao, Hai-Tao; Zuo, Yi-Qing; He, Hong-Ping; Li, Ling; null(郝小江)
刊名: JOURNAL OF NATURAL PRODUCTS
关键词: MEDICINAL-PLANTS ; CONSTITUENTS
英文摘要: Six new mixed lignan-neolignans and 20 known compounds were isolated from the whole plant of Tarenna attenuata. By analysis of physical and spectroscopic data, the structures of the new compounds were elucidated as (1R,5R,6R)-6-{4-O-[2-(1-(4-hydroxy-3-methoxyphenyl))glycerol]-3,5-dimethoxyphenyl}-3,7-dioxabicyclo[3.3.0]octan-2-one (1), 5' '-methoxyhedyotisol A (2), 4' '-O-(8-guaiacylglycerol)buddlenol A (3), 5' '-methoxy-4' '-O-(8-guaiacylglycerol)buddlenol A (4), 4,6-dimethoxy-5-hydroxy-3-hydroxymethyl-2-(3,4,5-trimethoxyphenyl)-2,3-dihydrobenzofuran (5), and 7-O-ethylguaiacylglycerol (6). Compounds 1, 5, 6, and 8 showed potent antioxidant activities against H2O2-induced impairment in PC12 cells, and compounds 1, 2, 5, and 7 scavenged DPPH radical strongly with IC50 values of 72, 87, 45, and 55 mu M, respectively.
出版日期: 2007-04-01
卷号: 70, 期号:4, 页码:521-525
DOI标识: 10.1021/np0603931
语种: 英语
ISSN号: 0163-3864
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/2085
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China
2.Second Mil Med Univ, Dept Nat Prod Chem, Sch Pharm, Shanghai 200433, Peoples R China
3.Kunming Med Coll, Yunnan Pharmacol Labs Nat Prod, Kunming 650031, Peoples R China
4.Guiyang Med Coll, Sch Pharm, Guiyang 550004, Peoples R China

Recommended Citation:
Yang, XW; Zhao, PJ; Ma, YL; Xiao, HT; Zuo, YQ; He, HP; Li, L; Hao, XJ.Mixed lignan-neolignans from Tarenna attenuata,JOURNAL OF NATURAL PRODUCTS,2007,70(4):521-525
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