Mixed lignan-neolignans from Tarenna attenuata
Yang, Xian-Wen; Zhao, Pei-Ji; Ma, Yan-Lin; Xiao, Hai-Tao; Zuo, Yi-Qing; He, Hong-Ping; Li, Ling; Hao, Xiao-Jiang
2007-04-01
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号70期号:4页码:521-525
摘要Six new mixed lignan-neolignans and 20 known compounds were isolated from the whole plant of Tarenna attenuata. By analysis of physical and spectroscopic data, the structures of the new compounds were elucidated as (1R,5R,6R)-6-{4-O-[2-(1-(4-hydroxy-3-methoxyphenyl))glycerol]-3,5-dimethoxyphenyl}-3,7-dioxabicyclo[3.3.0]octan-2-one (1), 5' '-methoxyhedyotisol A (2), 4' '-O-(8-guaiacylglycerol)buddlenol A (3), 5' '-methoxy-4' '-O-(8-guaiacylglycerol)buddlenol A (4), 4,6-dimethoxy-5-hydroxy-3-hydroxymethyl-2-(3,4,5-trimethoxyphenyl)-2,3-dihydrobenzofuran (5), and 7-O-ethylguaiacylglycerol (6). Compounds 1, 5, 6, and 8 showed potent antioxidant activities against H2O2-induced impairment in PC12 cells, and compounds 1, 2, 5, and 7 scavenged DPPH radical strongly with IC50 values of 72, 87, 45, and 55 mu M, respectively.
关键词Medicinal-plants Constituents
学科领域Plant Sciences ; Chemistry ; Medicinal ; Pharmacology & Pharmacy
DOI10.1021/np0603931
收录类别SCI ; IC
语种英语
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000246007200005
引用统计
被引频次:47[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/2085
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China
2.Second Mil Med Univ, Dept Nat Prod Chem, Sch Pharm, Shanghai 200433, Peoples R China
3.Kunming Med Coll, Yunnan Pharmacol Labs Nat Prod, Kunming 650031, Peoples R China
4.Guiyang Med Coll, Sch Pharm, Guiyang 550004, Peoples R China
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Yang, Xian-Wen,Zhao, Pei-Ji,Ma, Yan-Lin,et al. Mixed lignan-neolignans from Tarenna attenuata[J]. JOURNAL OF NATURAL PRODUCTS,2007,70(4):521-525.
APA Yang, Xian-Wen.,Zhao, Pei-Ji.,Ma, Yan-Lin.,Xiao, Hai-Tao.,Zuo, Yi-Qing.,...&Hao, Xiao-Jiang.(2007).Mixed lignan-neolignans from Tarenna attenuata.JOURNAL OF NATURAL PRODUCTS,70(4),521-525.
MLA Yang, Xian-Wen,et al."Mixed lignan-neolignans from Tarenna attenuata".JOURNAL OF NATURAL PRODUCTS 70.4(2007):521-525.
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