Triterpenoid saponins from Metadina trichotoma
Zhang, Yu-Mei; Tan, Ning-Hua; Huang, Huo-Qiang; Zeng, Guang-Zhi
2007-05-01
Source PublicationZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
ISSN0932-0776
Volume62Issue:5Pages:745-748
AbstractTwo new 27-nor-triterpene glycosides, pyrocincholic acid 3 beta-O-beta-D-glucopyranosyl-(1 -> 4)beta-D-quinovopyranosyl-28-O-beta-D-glucopyranoside (Metatrichoside A, 1), pyrocincholic acid 3 beta-O-beta-D-glucopyranosyl-(1 -> 4)-beta-D-quinovopyranosyl-28-O-beta-D-glucopyranosyl-(1 -> 6)-beta-Dglucopyranoside (Metatrichoside B, 2), together with pyrocincholic acid 3 beta-O-beta-D-quinovopyranosyl-28-O-beta-D-glucopyranoside (3), pyrocincholic acid 3 beta-O-beta-D-quinovopyranosyl-28-O-beta-D-glucopyranosyl-(1 -> 6)-beta-D-glucopyranoside (4), quinovic acid 3 beta-O-beta-D-quinovopyranoside (5), quinovic acid 3 beta-O-beta-D-quinovopyranosyl-28-O-beta-D-glucopyranoside (6), quinovic acid 3 beta-O-beta-D-glucopyranoside (7) and quinovic acid 3 beta-O-beta-D-glueopyranosyl-28-O-beta-D-glucopyranoside (8) were isolated from the barks of Metadina trichotoma. Their structures were mainly determined by mass spectrometric and 1D and 2D NMR spectroscopic methods. Compound 5 and 6 showed cytotoxic activities towards the A549 non-small-cell lung cancer cell line (IC50 = 8.43 and 6.06 mu m), and the methanol extract inhibited the activity of cathepsin B with an IC50 value of 0.77 mu g mL(-1).
KeywordMetadina Trichotoma Triterpenoid Saponins Metatrichoside a Metatrichoside b
Subject AreaChemistry ; Inorganic & Nuclear ; Chemistry ; Organic
Indexed BySCI ; IC
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Inorganic & Nuclear ; Chemistry, Organic
WOS IDWOS:000247299400021
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/2073
Collection植物化学与西部植物资源持续利用国家重点实验室
AffiliationChinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Zhang, Yu-Mei,Tan, Ning-Hua,Huang, Huo-Qiang,et al. Triterpenoid saponins from Metadina trichotoma[J]. ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES,2007,62(5):745-748.
APA Zhang, Yu-Mei,Tan, Ning-Hua,Huang, Huo-Qiang,&Zeng, Guang-Zhi.(2007).Triterpenoid saponins from Metadina trichotoma.ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES,62(5),745-748.
MLA Zhang, Yu-Mei,et al."Triterpenoid saponins from Metadina trichotoma".ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES 62.5(2007):745-748.
Files in This Item: Download All
File Name/Size DocType Version Access License
201109210024.pdf(34KB) 开放获取--View Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Zhang, Yu-Mei]'s Articles
[Tan, Ning-Hua]'s Articles
[Huang, Huo-Qiang]'s Articles
Baidu academic
Similar articles in Baidu academic
[Zhang, Yu-Mei]'s Articles
[Tan, Ning-Hua]'s Articles
[Huang, Huo-Qiang]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Zhang, Yu-Mei]'s Articles
[Tan, Ning-Hua]'s Articles
[Huang, Huo-Qiang]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: 201109210024.pdf
Format: Adobe PDF
This file does not support browsing at this time
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.