Antimicrobial and cytotoxic constituents from native Cameroonian medicinal plant Hypericum riparium | |
Tala, Michel Feussi1; Talontsi, Ferdinand Mouafo2; Zeng, Guang-Zhi1; Wabo, Hippolyte Kamdem3; Tan, Ning-Hua1; Spiteller, Michael2; Lane, Pierre3 | |
2015-04-01 | |
发表期刊 | FITOTERAPIA |
卷号 | 102页码:149-155 |
摘要 | Bioassay guided fractionation of Hypericum riparium leaves extract has resulted in the isolation and characterization of three new compounds namely chipericumin E (1), hyperenone C (3), and hyperixanthone (5), together with twenty known compounds. Their structures were elucidated based on comprehensive interpretation of spectroscopic and spectrometric data. Compounds 1-4, and 6-8 displayed moderate antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) and cytotoxic effects on the human gastric cell line BGC-823 with IC50 values ranging from 6.54 to 18.50 mu M. (C) 2015 Elsevier B.V. All rights reserved. |
关键词 | Hypericum Riparium Phloroglucinols Butenolide Xanthones Antimicrobial Cytotoxicity |
DOI | 10.1016/j.fitote.2015.02.006 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000353742600021 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/20682 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.TU Dortmund, Chair Environm Chem & Analyt Chem, Fac Chem, Inst Environm Res INFU, D-44221 Dortmund, Germany 3.Univ Dschang, Dept Chem, Dschang, Cameroon |
推荐引用方式 GB/T 7714 | Tala, Michel Feussi,Talontsi, Ferdinand Mouafo,Zeng, Guang-Zhi,et al. Antimicrobial and cytotoxic constituents from native Cameroonian medicinal plant Hypericum riparium[J]. FITOTERAPIA,2015,102:149-155. |
APA | Tala, Michel Feussi.,Talontsi, Ferdinand Mouafo.,Zeng, Guang-Zhi.,Wabo, Hippolyte Kamdem.,Tan, Ning-Hua.,...&Lane, Pierre.(2015).Antimicrobial and cytotoxic constituents from native Cameroonian medicinal plant Hypericum riparium.FITOTERAPIA,102,149-155. |
MLA | Tala, Michel Feussi,et al."Antimicrobial and cytotoxic constituents from native Cameroonian medicinal plant Hypericum riparium".FITOTERAPIA 102(2015):149-155. |
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