Antimicrobial and cytotoxic constituents from native Cameroonian medicinal plant Hypericum riparium
Tala, Michel Feussi1; Talontsi, Ferdinand Mouafo2; Zeng, Guang-Zhi1; Wabo, Hippolyte Kamdem3; Tan, Ning-Hua1; Spiteller, Michael2; Lane, Pierre3
2015-04-01
发表期刊FITOTERAPIA
卷号102页码:149-155
摘要Bioassay guided fractionation of Hypericum riparium leaves extract has resulted in the isolation and characterization of three new compounds namely chipericumin E (1), hyperenone C (3), and hyperixanthone (5), together with twenty known compounds. Their structures were elucidated based on comprehensive interpretation of spectroscopic and spectrometric data. Compounds 1-4, and 6-8 displayed moderate antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) and cytotoxic effects on the human gastric cell line BGC-823 with IC50 values ranging from 6.54 to 18.50 mu M. (C) 2015 Elsevier B.V. All rights reserved.
关键词Hypericum Riparium Phloroglucinols Butenolide Xanthones Antimicrobial Cytotoxicity
收录类别SCI
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/20682
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.TU Dortmund, Chair Environm Chem & Analyt Chem, Fac Chem, Inst Environm Res INFU, D-44221 Dortmund, Germany
3.Univ Dschang, Dept Chem, Dschang, Cameroon
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Tala, Michel Feussi,Talontsi, Ferdinand Mouafo,Zeng, Guang-Zhi,et al. Antimicrobial and cytotoxic constituents from native Cameroonian medicinal plant Hypericum riparium[J]. FITOTERAPIA,2015,102:149-155.
APA Tala, Michel Feussi.,Talontsi, Ferdinand Mouafo.,Zeng, Guang-Zhi.,Wabo, Hippolyte Kamdem.,Tan, Ning-Hua.,...&Lane, Pierre.(2015).Antimicrobial and cytotoxic constituents from native Cameroonian medicinal plant Hypericum riparium.FITOTERAPIA,102,149-155.
MLA Tala, Michel Feussi,et al."Antimicrobial and cytotoxic constituents from native Cameroonian medicinal plant Hypericum riparium".FITOTERAPIA 102(2015):149-155.
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