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题名: Unusual cycloartane triterpenoids from Kadsura ananosma
作者: Yang,Jian-Hong ; Pu,Jian-Xin ; Wen,Jin ; Li,Xiao-Nian ; He,Fei ; Su,Jia ; null(李艳) ; Sun,Han-Dong
刊名: PHYTOCHEMISTRY
出版日期: 2015
卷号: 109, 页码:36-42
关键词: Kadsura ananosma ; Schisandraceae ; Cycloartane triterpenoids ; Ananosins
学科分类: Biochemistry & Molecular Biology; Plant Sciences
DOI: 10.1016/j.phytochem.2014.10.014
通讯作者: Pu,JX (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Yunnan,Peoples R China. ; pujianxin@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn
文章类型: Article
英文摘要: Five 3,4-seco-cycloartane triterpenoids were isolated from the stems of Kadsura ananosma, two of which had rearranged 5/6 consecutive carbocycle rings C/D (trivially named ananosins A (1) and B (2)), one had a migrated CH3-18 (named ananosins C (3)), and two were analogs, ananosins D (4) and E (5). Their structures were characterized by comprehensive spectroscopic analysis, especially using 2D NMR spectra. A biogenetic pathway to 1 was proposed. These 5 compounds, together with 5 known analogs isolated from the same origin, were evaluated for their cytotoxicity against HL-60, SMMC-7721, A-549, PANC-1, and SK-BR-3 human cancer cells, but were inactive, (C) 2014 Elsevier Ltd. All rights reserved.
研究领域[WOS]: Biochemistry & Molecular Biology ; Plant Sciences
关键词[WOS]: DIBENZOCYCLOOCTADIENE LIGNANS ; UNIQUE SKELETON ; COCCINEA ; DILACTONES ; LONGIPEDUNCULATA ; INTERIOR ; PHILIPPINENSIS ; HETEROCLITA ; ACIDS
收录类别: SCI
项目资助者: National Natural Science Foundation of China [21322204] ; Major State Basic Research Development Program of China [2009CB522300, 2009CB940900] ; Young Academic and Technical Leader Rising Foundation of Yunnan Province ; Science and technology plan project of Yunnan Province [2008GA031] ; CAS action-plan for West Development [KZCX2-XB2-15]
语种: 英语
WOS记录号: WOS:000347769400004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/20621
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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