Unusual cycloartane triterpenoids from Kadsura ananosma
Yang,Jian-Hong; Pu,Jian-Xin; Wen,Jin; Li,Xiao-Nian; He,Fei; Su,Jia; Li,Yan; Sun,Han-Dong; Pu,JX (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Yunnan,Peoples R China.; pujianxin@mail.kib.ac.cn; hdsun@mail.kib.ac.cn
2015
发表期刊PHYTOCHEMISTRY
卷号109页码:36-42
摘要Five 3,4-seco-cycloartane triterpenoids were isolated from the stems of Kadsura ananosma, two of which had rearranged 5/6 consecutive carbocycle rings C/D (trivially named ananosins A (1) and B (2)), one had a migrated CH3-18 (named ananosins C (3)), and two were analogs, ananosins D (4) and E (5). Their structures were characterized by comprehensive spectroscopic analysis, especially using 2D NMR spectra. A biogenetic pathway to 1 was proposed. These 5 compounds, together with 5 known analogs isolated from the same origin, were evaluated for their cytotoxicity against HL-60, SMMC-7721, A-549, PANC-1, and SK-BR-3 human cancer cells, but were inactive, (C) 2014 Elsevier Ltd. All rights reserved.
关键词Kadsura Ananosma Schisandraceae Cycloartane Triterpenoids Ananosins
资助信息National Natural Science Foundation of China [21322204]; Major State Basic Research Development Program of China [2009CB522300, 2009CB940900]; Young Academic and Technical Leader Rising Foundation of Yunnan Province; Science and technology plan project of Yunnan Province [2008GA031]; CAS action-plan for West Development [KZCX2-XB2-15]
学科领域Biochemistry & Molecular Biology ; Plant Sciences
DOI10.1016/j.phytochem.2014.10.014
收录类别SCI
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Plant Sciences
WOS记录号WOS:000347769400004
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/20621
专题植物化学与西部植物资源持续利用国家重点实验室
通讯作者Pu,JX (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Yunnan,Peoples R China.; pujianxin@mail.kib.ac.cn; hdsun@mail.kib.ac.cn
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Yang,Jian-Hong,Pu,Jian-Xin,Wen,Jin,et al. Unusual cycloartane triterpenoids from Kadsura ananosma[J]. PHYTOCHEMISTRY,2015,109:36-42.
APA Yang,Jian-Hong.,Pu,Jian-Xin.,Wen,Jin.,Li,Xiao-Nian.,He,Fei.,...&hdsun@mail.kib.ac.cn.(2015).Unusual cycloartane triterpenoids from Kadsura ananosma.PHYTOCHEMISTRY,109,36-42.
MLA Yang,Jian-Hong,et al."Unusual cycloartane triterpenoids from Kadsura ananosma".PHYTOCHEMISTRY 109(2015):36-42.
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