Constituents from the edible Chinese black ants (Polyrhachis dives) showing protective effect on rat mesangial cells and anti-inflammatory activity

doi:10.1016/j.foodres.2014.11.022

	Constituents from the edible Chinese black ants (Polyrhachis dives) showing protective effect on rat mesangial cells and anti-inflammatory activity
	Tang,Jian-Jun; Fang,Ping; Xia,Hou-Lin; Tu,Zheng-Chao; Hou,Bi-Yu; Yan,Yong-Ming; Di,Lei; Zhang,Li; Cheng,Yong-Xian; Zhang,L (reprint author),132 Lanhei Rd,Kunming 650201,Peoples R China.; zhangli@imm.ac.cn; yxcheng@mail.kib.ac.cn
	2015
发表期刊	FOOD RESEARCH INTERNATIONAL
卷号	67 页码:163-168
摘要	Accumulated data have emphasized the critical role of inflammation in the pathogenesis of diabetic nephropathy (DN). Chinese black ants (Polyrhachis dives), an edible insect, are well-known for kidney tonifying and anti-inflammatory properties. We have conducted a study that led to isolation of thirteen nonpeptide nitrogen containing compounds from P. dives. Most of these substances possess pyridine moieties and three are alkaloids isolated for the first time from natural sources. Based on ethnopharmacological considerations, the biological potentials of these substances were determined utilizing multiple assays including renal protection, T-, B-lymphocyte proliferation, TNF-alpha, COX-1, COX-2, and Jak3 kinase inhibition. The finding that several members of this family display activities in one or more of these assays has led to the elucidation of part of the chemical profile of P. dives in terms of non-peptide, small-molecule components. (C) 2014 Elsevier Ltd. All rights reserved.
关键词	Polyrhachis Dives Formicidae Chinese Black Ants Diabetic Nephropathy Alkaloids
学科领域	Food Science & Technology
DOI	10.1016/j.foodres.2014.11.022
收录类别	SCI
语种	英语
WOS记录号	WOS:000348619600019
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/20608
专题	植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Zhang,L (reprint author),132 Lanhei Rd,Kunming 650201,Peoples R China.; zhangli@imm.ac.cn; yxcheng@mail.kib.ac.cn
推荐引用方式 GB/T 7714	Tang,Jian-Jun,Fang,Ping,Xia,Hou-Lin,et al. Constituents from the edible Chinese black ants (Polyrhachis dives) showing protective effect on rat mesangial cells and anti-inflammatory activity[J]. FOOD RESEARCH INTERNATIONAL,2015,67:163-168.
APA	Tang,Jian-Jun.,Fang,Ping.,Xia,Hou-Lin.,Tu,Zheng-Chao.,Hou,Bi-Yu.,...&yxcheng@mail.kib.ac.cn.(2015).Constituents from the edible Chinese black ants (Polyrhachis dives) showing protective effect on rat mesangial cells and anti-inflammatory activity.FOOD RESEARCH INTERNATIONAL,67,163-168.
MLA	Tang,Jian-Jun,et al."Constituents from the edible Chinese black ants (Polyrhachis dives) showing protective effect on rat mesangial cells and anti-inflammatory activity".FOOD RESEARCH INTERNATIONAL 67(2015):163-168.

条目包含的文件		下载所有文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
Tang-2015-Constituen（542KB）			开放获取	CC BY-NC-ND	浏览下载