Constituents from the edible Chinese black ants (Polyrhachis dives) showing protective effect on rat mesangial cells and anti-inflammatory activity
Tang,Jian-Jun; Fang,Ping; Xia,Hou-Lin; Tu,Zheng-Chao; Hou,Bi-Yu; Yan,Yong-Ming; Di,Lei; Zhang,Li; Cheng,Yong-Xian; Zhang,L (reprint author),132 Lanhei Rd,Kunming 650201,Peoples R China.; zhangli@imm.ac.cn; yxcheng@mail.kib.ac.cn
2015
Source PublicationFOOD RESEARCH INTERNATIONAL
Volume67Pages:163-168
AbstractAccumulated data have emphasized the critical role of inflammation in the pathogenesis of diabetic nephropathy (DN). Chinese black ants (Polyrhachis dives), an edible insect, are well-known for kidney tonifying and anti-inflammatory properties. We have conducted a study that led to isolation of thirteen nonpeptide nitrogen containing compounds from P. dives. Most of these substances possess pyridine moieties and three are alkaloids isolated for the first time from natural sources. Based on ethnopharmacological considerations, the biological potentials of these substances were determined utilizing multiple assays including renal protection, T-, B-lymphocyte proliferation, TNF-alpha, COX-1, COX-2, and Jak3 kinase inhibition. The finding that several members of this family display activities in one or more of these assays has led to the elucidation of part of the chemical profile of P. dives in terms of non-peptide, small-molecule components. (C) 2014 Elsevier Ltd. All rights reserved.
KeywordPolyrhachis Dives Formicidae Chinese Black Ants Diabetic Nephropathy Alkaloids
Subject AreaFood Science & Technology
DOI10.1016/j.foodres.2014.11.022
Indexed BySCI
Language英语
WOS Research AreaFood Science & Technology
WOS IDWOS:000348619600019
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/20608
Collection植物化学与西部植物资源持续利用国家重点实验室
Corresponding AuthorZhang,L (reprint author),132 Lanhei Rd,Kunming 650201,Peoples R China.; zhangli@imm.ac.cn; yxcheng@mail.kib.ac.cn
Recommended Citation
GB/T 7714
Tang,Jian-Jun,Fang,Ping,Xia,Hou-Lin,et al. Constituents from the edible Chinese black ants (Polyrhachis dives) showing protective effect on rat mesangial cells and anti-inflammatory activity[J]. FOOD RESEARCH INTERNATIONAL,2015,67:163-168.
APA Tang,Jian-Jun.,Fang,Ping.,Xia,Hou-Lin.,Tu,Zheng-Chao.,Hou,Bi-Yu.,...&yxcheng@mail.kib.ac.cn.(2015).Constituents from the edible Chinese black ants (Polyrhachis dives) showing protective effect on rat mesangial cells and anti-inflammatory activity.FOOD RESEARCH INTERNATIONAL,67,163-168.
MLA Tang,Jian-Jun,et al."Constituents from the edible Chinese black ants (Polyrhachis dives) showing protective effect on rat mesangial cells and anti-inflammatory activity".FOOD RESEARCH INTERNATIONAL 67(2015):163-168.
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