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题名: Compounds from the Chinese black ant (Polyrhachis dives) and NMR behavior of the isomers with formamide group
作者: Tang,Jian-Jun ; Luo,Qi ; Di,Lei ; Zhang,Li ; Lu,Qing ; Hou,Bo ; Zuo,Zhi-Li ; Xia,Hou-Lin ; Ma,Xiu-Jing ; null(程永现)
刊名: JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
出版日期: 2015
卷号: 17, 期号:1, 页码:20-26
关键词: black ant ; Polyrhachis dives ; amide bond ; N-containing compound ; immunosuppressive activity
学科分类: Plant Sciences; Chemistry, Applied; Chemistry, Medicinal; Pharmacology & Pharmacy
DOI: 10.1080/10286020.2014.966698
通讯作者: Xia,HL (reprint author),Chengdu Univ Tradit Chinese Med,Coll Pharm,Chengdu 610075,Peoples R China. ; 18980555665@163.com ; maxiujing@sina.com ; yxcheng@mail.kib.ac.cn
文章类型: Article
英文摘要: Two new dopamine derivatives divesamides A (1) and B (2), along with six known N-containing compounds were isolated from the Chinese black ant (Polyrhachis dives). Their structures were determined on the basis of spectroscopic methods. Compound 1 is a racemate, and chiral HPLC separation yielded a pair of antipodes. The absolute configuration of (+)-1 was assigned by a computational method. The double signals in the H-1 and C-13 NMR spectra of 2 that resulted from the presence of a formamide group were discussed. The T- and B-lymphocytes proliferation assay showed that 2 has moderate immunosuppressive activity toward T- and B-lymphocytes proliferation at a concentration of 20 mu M.
研究领域[WOS]: Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]: AMIDE BOND
收录类别: SCI
项目资助者: State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources
语种: 英语
WOS记录号: WOS:000348320400004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/20607
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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