Ethnopharmacological relevance: Piper wallichii (Miq.) Hand.-Mazz. is a medicinal plant used widely for the treatment of rheumatoid arthritis, inflammatory diseases, cerebral infarction and angina in China. Previous study showed that lignans and neolignans from Piper spp. had potential inhibitory activities on platelet aggregation. In the present study, we investigated the chemical constituents of Piper wallichii and their antithrombotic activities, to support its traditional uses.
; 973 Program of Ministry of Science and Technology of the People's Republic of China [2011CB915503]
; National Science and Technology Support Program of China [2013BAI11B02]
; Fourteenth Candidates of the Young Academic Leaders of Yunnan Province [2011CI044]
; West Light Foundation of the Chinese Academy of Sciences
1.Chinese Acad Sci, Kunming Inst Bot, State Key Laboratoty Phytochem & Plant Resources, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Univ Mississippi, Sch Pharm, Natl Ctr Nat Prod Res, University, MS 38677 USA