Antiviral isocoumarins from the roots and stems of Nicotiana tabacum
Shang, Shan-Zhai1,2; Xu, Wen-Xiu1,3,4; Li, Lan1,3,4; Tang, Jian-Guo1; Zhao, Wei1; Lei, Ping1; Miao, Ming-Ming1; Sun, Han-Dong2; Pu, Jian-Xin2; Chen, Yong-Kuan1; Yang, Guang-Yu1; Chen,YK (reprint author),China Tobacco Yunnan Ind Co Ltd,Key Lab Tobacco Chem Yunnan Prov,Kunming 650231,Peoples R China.; cyk1966@163.com; ygy1110@163.com
2015-03-01
Source PublicationPHYTOCHEMISTRY LETTERS
Volume11Pages:53-56
AbstractThree new isocoumarin derivatives, tabaisocoumarins A-C (1-3), together with three known phenolic compounds (4-6), were isolated from the roots and stems of Nicotiana tabacum. Their structures were elucidated by spectroscopic methods, including extensive 1D- and 2D NMR techniques. Compounds 1-6 were evaluated for their anti-tobacco mosaic virus (anti-TMV) activities at the concentration of 20 mu M. Compound 2 exhibited anti-TMV activity with inhibition rate of 33.8%, which is higher than that of positive control, ningnanmycin. The other compounds also showed potential anti-TMV activities with inhibition rates in the range of 18.7-28.5%, respectively. (C) 2014 Published by Elsevier B.V. on behalf of Phytochemical Society of Europe.
KeywordNicotiana Tabacum Isocoumarin Derivatives Tabaisocoumarins A-c Anti-tobacco Mosaic Virus Activity
Subject AreaBiochemistry & Molecular Biology ; Plant Sciences
DOI10.1016/j.phytol.2014.11.008
Indexed BySCI
Language英语
WOS IDWOS:000350569100011
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/20602
Collection植物化学与西部植物资源持续利用国家重点实验室
Corresponding AuthorChen,YK (reprint author),China Tobacco Yunnan Ind Co Ltd,Key Lab Tobacco Chem Yunnan Prov,Kunming 650231,Peoples R China.; cyk1966@163.com; ygy1110@163.com
Affiliation1.China Tobacco Yunnan Ind Co Ltd, Key Lab Tobacco Chem Yunnan Prov, Kunming 650231, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
3.Kunming Med Univ, Sch Pharmaceut Sci, Kunming 650500, Yunnan, Peoples R China
4.Kunming Med Univ, Yunnan Key Lab Pharmacol Nat Prod, Kunming 650500, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Shang, Shan-Zhai,Xu, Wen-Xiu,Li, Lan,et al. Antiviral isocoumarins from the roots and stems of Nicotiana tabacum[J]. PHYTOCHEMISTRY LETTERS,2015,11:53-56.
APA Shang, Shan-Zhai.,Xu, Wen-Xiu.,Li, Lan.,Tang, Jian-Guo.,Zhao, Wei.,...&ygy1110@163.com.(2015).Antiviral isocoumarins from the roots and stems of Nicotiana tabacum.PHYTOCHEMISTRY LETTERS,11,53-56.
MLA Shang, Shan-Zhai,et al."Antiviral isocoumarins from the roots and stems of Nicotiana tabacum".PHYTOCHEMISTRY LETTERS 11(2015):53-56.
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